To focus on specific sub specialties check/uncheck boxes on left
25%
18%
11%
11%
9%
7%
5%
5%
5%
4%
2%
Displaying
100%
6%
Synopsis: 82 patients with symptomatic knee osteoarthritis were randomized to either treatment with a topical flaxseed oil preparation or to placebo.Patients were to apply allocated treatment three times daily for 6 weeks.The outcome measure was the Knee Injury and Osteoarthritis Outcome Score (KOOS). Improvement in each... Read More »
Level 2 RCT
4%
Synopsis: 1583 patients with symptomatic knee osteoarthritis were randomized to either glucosamine monotherapy, chondroitin monotherapy, combined glucosamine and chondroitin therapy, celecoxib 200mg daily, or placebo.Patients were assessed over 24 weeks of treatment.In the primary analysis, only the celecoxib group demonstrated a significantly higher rate of patients attaining the primary efficacy endpoint - a reduction of WOMAC pain by a minimum of 20% relative to baseline - compared to placebo. However, when only... Read More »
RCT
4%
Synopsis: 18 randomized controlled trials were included in this meta-analysis which sought to evaluate the efficacy of cupping intervention for treatment of neck pain.Analyses were separated based on control group: inactive or active intervention.Compared to both inactive control intervention and active control interventions, there was low to very low strength evidence that cupping therapy significantly reduced pain and disability. In addition, when... Read More »
Level 1 Meta Analysis
4%
Synopsis: 60 patients with type III-IV acromioclavicular joint dislocation were randomized to either surgical intervention with open reduction and tunneled suspensory device fixation (ORTSD group) or to nonoperative treatment.The purpose of this study was to compare disability and function over the first year of follow-up. Results on the... Read More »
Level 2 RCT
3%
Synopsis: 9 studies (8 RCTs, 1 controlled clinical trial) were selected for a systematic review of elderly patients with a proximal humerus fracture.The goal of this study was to determine whether surgical or nonoperative treatment is the optimal intervention in patients over the age of 60.Operative treatments identified in the included trials were the tension band technique, locking plates, pinning and hemiarthroplasty.The results of this review indicated that many studies did not find a significant difference in functional outcomes when comparing locking plates or tension bands to nonoperative treatment at 1 year.There was a significantly better health-related quality of life and Euroqol-5D in patients that received a hemiarthroplasty compared to the nonoperative group for patients with 4-part fractures.Complications were common in the operative treatment groups. This study highlights... Read More »
Level 2 Meta Analysis
3%
Synopsis: 147 patients with a diagnosis of plantar fasciities were randomized to injection therapy with either 40mg of micronized dehydrated human amnion/chorion membrane (dHACM) in 1mL saline or to placebo saline alone.In addition to injection, all patients were managed with orthoses for 2 weeks after injection.Patients were assessed primarily for change in visual analog pain score (VAS pain) from baseline to 3 months post-injection. Results demonstrated a... Read More »
Level 2 RCT
3%
Synopsis: 120 patients with Kellgren-Lawrence grade II-IV knee osteoarthritis were randomized to intraarticular injection with either a combination of hyaluronic acid and corticosteroid, or hyaluronic acid alone.Patients were followed-up for 6 months posttreatment for outcome related to pain on a visual analog scale and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).Between groups, bth VAS pain and WOMAC assessments significantly favoured the HA+CS group compared to the HA alone group at 1 week, 1 month, and 3 months; differences between groups at 6 months were not significant. However, when the... Read More »
Level 2 RCT
3%
Synopsis: 319 patients with single-level cervical disc disease and scheduled for anterior cervical discectomy and fusion were randomized to the surgery completed with either an allograft (i-Factorâ„¢ Peptide Enhanced Bone Graft; Cerapedics Inc.) or local bone autograft.Patients were assessed over 1- and 2-year follow-up for rate of fusion success, a composite endpoint of overall success, clinical scores, and incidence of adverse events.Rate of fusion success was similar between the groups after 12 and 24 months.Rate of overall success (composite endpoint) was significantly higher in the i-Factor group compared to the autograft group at 12 and 24 months.Clinical scores demonstrated no significant differences between groups after 24 months, and most adverse events demonstrated similar rates between groups. Rate of superficial... Read More »
Level 2 RCT
3%
Synopsis: 75 patient scheduled for arthroscopic repair of a supraspinatus tearm were randomized to repair with or without augmentation with platelet-rich plasma.The current study sought to compare clinical scores and healing on MRI at 60-month follow-up. Results demonstrated no... Read More »
Level 2 RCT
3%
Synopsis: 373 patients scheduled for total knee arthroplasty were randomized to a postoperative analgesia regimen featuring either intraoperative periarticular infiltration analgesia with liposomal bupviacaine, or a preoperative femoral nerve block.Patients were assessed for analgesic and functional measures at 12-hour intervals following surgery, as well as at 6-week, 3-month, and 1-year follow-up.Outcomes demonstrated significant differences in favour of the FNB group for pain scores and knee range of motion at 12 and 24 hours after surgery, and a significant differences in favour of the LB PAI group in the ability to perform the straight leg raise test at 12 hours.The differences between groups in these outcome measures at subsequent follow-up points were not significant. In addition, no... Read More »
Level 2 RCT