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Synopsis: 109 patients with a moderate, dorsally displaced distal radius fracture (Colles') were randomized to two different conservative management protocols after closed reduction.One group was treated with plaster cast immobilization for 10 days followed by elastic bandaging, while the other group was treated with 1 month (range 4-5 weeks) of plaster cast immobilization. Radiographic results found... Read More »
Author verified Level 2 RCT
12%
Synopsis: 323 patients with a distal radial fracture were randomized to receive a closed reduction followed by injection of Norian Skeletal Repair System (SRS) cement or a closed reduction with a cast or external fixator (control).Patients were assessed clinically and radiographically through 12 months.At 6-8 weeks, clinical findings were significantly better in the Norian group than the control group in terms of grip strength, wrist range of motion, digital motion, use of the hand, social and emotional function, and swelling.These differences were not seen by 1 year.No differences were seen in the total number of complications, including loss of reduction. But the infection... Read More »
Level 2 RCT
12%
Synopsis: 27 randomized controlled trials that examined 9 different active treatments were included in this network meta-analysis to evaluate the efficacy of various treatments compared to placebo plus calcium and vitamin D in the treatment of patients with glucocorticoid-induced osteoporosis.Outcomes assessed in this network meta-analysis were incidence of vertebral fractures, incidence of non-vertebral fractures, and bone mineral density at the lumbar spine and femoral neck.The results of this analysis indicate that only etidronate, risedronate, and teriparatide were associated with a significantly decreased risk of vertebral fracture relative to placebo plus calcium and vitamin D.No treatments demonstrated a reduction in the risk of non-vertebral fracture when compared to placebo plus calcium and vitamin D. Read More »
Level 2 Meta Analysis
12%
Synopsis: Seven randomized controlled trials evaluating the efficacy of exercise therapy and/or manual therapy relative to control intervention for patients with hip osteoarthritis were included in this meta-analysis.Control groups among the included studies ranged from usual care from general practitioners, patient education, and waiting list control.High-quality evidence indicated that exercise therapy significantly improved pain and physical function post-treatment and at follow-up compared to control interventions. While manual therapy... Read More »
Level 2 Meta Analysis
12%
Synopsis: 111 patients with Kellgren-Lawrence grade I-IV symptomatic knee osteoarthritis were randomized to three weekly intraarticular injections of either leukocyte-poor platelet-rich plasma (LP-PRP) or hyaluronic acid.Patients were assessed for pain and function over a 52-week follow-up.The primary outcome measure, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score, demonstrated no significant difference between groups at any time point.In contrast, pain scores on a visual analog scale (VAS) demonstrated significantly lower pain in the LP-PRP group compared to the HA group at 24- and 52-week follow-up. Similarly International Knee... Read More »
Author verified Level 2 RCT
12%
Synopsis: Six randomized controlled trials (231 patients) were included in this analysis comparing short-term pain and functional outcome between a specific exercise program and general exercise program in the management of patients with subacromial impingement syndrome.Compiling data at 4-8 week follow-up, results demonstrated no significant differences between the two strategies in pain during activity, or in functional outcome. Further high-quality trials... Read More »
Level 1 Meta Analysis
12%
Synopsis: 41 patients with primary frozen shoulder who received treatment with hydrodilatation were randomized to either participate in a 4-week supervised physiotherapy program afterward in addition to a home exercise therapy program, or to home exercises alone.Patients were assessed for shoulder function on the Oxford Shoulder Score, pain, and range of motion at 4 weeks, 3 months, 6 months, and 12-month follow-up. Results demonstrated no... Read More »
Level 2 RCT
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