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Synopsis: 9 randomized controlled trials were included in this meta-analysis, comparing arthroscopic surgery to conservative management for the treatment of degenerative meniscal tears in patients over the age of 40 years.Outcomes of interest included knee pain and knee function. The results from... Read More »
Level 1 Meta Analysis
9%
Synopsis: 9 studies (7 randomized control trials, 2 non-randomized control trials) comparing a home-based, supervised exercise program (HET) to either a hospital-based, supervised exercise program (SET) or to simple, unsupervised "go home and walk" advice (GHWA) to treat intermittent claudication were included in this systematic review.The purpose of the review was to determine if a home-based exercise program benefited patient walking capacity and quality of life more than the comparative treatments.Qualitative analysis found HET to provide generally better results compared to GHWA.When compared to SET, HET showed somewhat worse results for pain-free walking capacity and health-related quality of life, but better daily life walking capacity. Outcomes were inconsistent... Read More »
Level 2 Meta Analysis
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Synopsis: 29 studies were included in this meta-analysis comparing operative and non-operative treatment for acute Achilles tendon ruptures.The primary outcome of interest was the rate of re-rupture.Secondary outcomes included the rate of complications, functional outcomes, time to return to sports and time to return to work.The results revealed a significantly lower rate of re-rupture, but a higher rate of complications, in the operative group compared to the non-operative group.Similar findings to the primary analyses were observed in the sensitivity analyses based on early and late weight bearing status, high quality studies and studies conducted after the year 2000.There were no significant differences in re-rupture rate in studies utilizing accelerated functional rehabilitation. There was no... Read More »
Level 1 Meta Analysis
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Synopsis: 8 ACE Reports (all randomized controlled trials) from the OrthoEvidence database were included in this review/meta-analysis examining the effect of arthroscopic surgery and physical therapy in the treatment of degenerative tears of the meniscus and knee osteoarthritis.The purpose of this review was to determine if any differences in outcome were demonstrated between arthroscopy followed by physical therapy versus physical therapy alone, regarding pain, function, satisfaction, adverse events, or osteoarthritis progression.Pain results were pooled at 3 different time point: 2-3 months, 6 months, and 12-24 months postintervention.At short-term (2-3 months) and long-term (12-24 months) follow-up, pain was similar between groups, with no significant difference observed.There tended to be less pain experienced at 6 months following arthroscopy, however this only reached significance in the KOOS pain outcome and the clinical importance of this observation is unknown.Assessments of functional outcome, either pooled or qualitative, suggested no significant difference between groups as well. The rate of... Read More »
ACE Review
2%
Synopsis: 33 patients with trapeziometacarpal osteoarthritis were randomized to two intraarticular injections of either platelet-rich plasma or corticosteroid.Patients were assessed for pain on a visual analog scale after 3 months and 12 months. Results demonstrated a... Read More »
Conference Report
2%
Synopsis: Four randomized controlled trials were selected for inclusion in this meta-analysis which compared results in hip osteoarthritis treatment between platelet-rich plasma injections and hyaluronic acid injections.Data on patient-reported pain and function scores were pooled at 2, 6 and 12 months post-injection. The only significant... Read More »
Level 1 Meta Analysis
2%
Synopsis: The authors performed a systematic review and meta-analysis of five randomized controlled trials, all of which compared intra-articular viscosupplementation to placebo for patients with hip osteoarthritis.They had a total sample size of 591 patients followed at 3 different time points: 7-14 days, 28-30 days, and final follow-up.Outcomes included pain (Numeric Rating Scale, Visual Analogue Scale, and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain score) and function (WOMAC Function and Lequesne). Though some studies... Read More »
Level 1 Meta Analysis
1%
Synopsis: 100 patients with chronic lateral epicondylitis were randomized to receive either leukocyte-enriched platelet-rich plasma (PRP) or a corticosteroid treatment, as a control.This was performed in order to determine the efficacy of PRP treatment in the recovery of postoperative function and pain relief.Patients were followed-up at two years to determine the effect on pain and function. Both pain and... Read More »
Author verified Level 1 RCT
1%
Synopsis: 80 obese patients with osteoarthritis of the knee were randomized to undergo a low-energy diet or a control diet, in order to assess the effects of rapid diet-induced weight loss on osteoarthritis. The results of the study revealed a 10% reduction in weight results and a 28% increase in knee function, which suggested that weight loss was an effective treatment method for osteoarthritis of the knee. Read More »
Author verified Level 2 RCT
1%
Synopsis: This meta-analysis included 7 studies comparing a proprioceptive exercise regime to a control (non-proprioceptive program or no treatment) in patients with knee osteoarthritis.From the 7 studies, there was a total of 560 patients.Results from the analysis indicated that proprioceptive exercise led to significantly greater outcomes for all functional assessments than a non-treatment control. However, compared to... Read More »
Level 1 Meta Analysis