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8%
Synopsis: Twenty-four patients with hamstring shortness were randomized to receive either a self-myofascial release program with a foam roller (n=12) or no intervention (control) (n=12).The primary outcome of this trial was to determine the effect of using a foam roller on the isokinetic hamstring-to-quadriceps strength ratio and range of motion after 8 weeks.The results of this trial showed significant improvements in the range of motion in the foam roller group at 8 weeks when compared to the control group. No significant differences... Read More »
Level 1 RCT
6%
Synopsis: Sixty-one patients with knee osteoarthritis were randomized to receive an open-label placebo with verbal suggestions indicating pain relief (n=21) or mood improvement (n=21), or no treatment (n=19).The primary outcomes of interest included knee pain and function (Numeric Rating Scale [NRS]; Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC]).Secondary outcomes of interest included course of pain and mood ratings, need for analgesics, global clinical improvement, quality of life, perceived stress, salivary cortisol, and heart rate variation.Outcomes were assessed after 21 days of intervention.Results revealed patients who received an open-label placebo had significantly lower NRS and WOMAC pain scores, as well as a greater perceived clinical improvement vs. Read More »
Author verified Level 1 RCT
4%
Synopsis: Fifty female recreational runners with medial tibial stress syndrome (shin splints) were randomized to receive an 18-week multimodal intervention program (icing, ankle stretching and strengthening, extracorporeal shockwave therapy) plus the use of arch support foot orthoses (n=25) or a sham orthoses (n=25).Outcomes of interest included pain intensity, condition severity, perceived treatment effect, and the Short-Form 36 (SF-36) quality of life questionnaire.Results revealed significantly greater improvement in pain intensity, condition severity, perceived treatment effect, and SF-36 physical function and bodily harm sub-scores in the foot orthoses group vs. Read More »
Level 1 RCT
3%
Synopsis: One hundred and twenty patients with lumbar facet joint syndrome due to osteoarthritis were randomized to receive an ultrasound-guided intra-articular injection of methylene blue (n=60) or diprospan (n=60).The primary outcome of interest was pain on a Numeric Rating Scale (NRS), measured up to 6 months post-operation.Secondary outcomes of interest included lumbar function, sleep quality, depression severity, treatment efficacy, post-operative analgesic consumption, and the incidence of complications.Results revealed significantly lower pain scores, better lumbar function and sleep quality, lower depression severity, and a lower incidence of hyperglycemia with methylene blue injection vs. Read More »
Level 1 RCT
3%
Synopsis: Sixty patients with myofascial pain syndrome were randomized to receive repeated trapezius muscle injections (TMI, n=30) or a TMI followed by an erector spinae plane block (ESPB).The primary outcome of interest was pain measured with a visual analogue scale.In both groups, the VAS scores decreased significantly from baseline. The combined TMI... Read More »
Level 1 RCT
3%
Synopsis: 14 randomized controlled trials with a total of 2796 knee osteoarthritis patients were included in this network meta-analysis comparing high molecular weight hyaluronic acid injection, low molecular weight hyaluronic acid injection, intra-articular corticosteroid injection, other FDA-approved conservative therapies, and intra-articular placebo injection.The outcome of interest was pooled pain scores, with minimal clinically important differences derived from previous literature and the American Academy of Orthopaedic Surgeons (AAOS) guidelines.Results of the meta-analysis found that high molecular weight hyaluronic acid injection was the highest ranked treatment, providing significantly greater pain relief vs.placebo injection that was possibly clinically significant. No other significant... Read More »
Meta Analysis
3%
Synopsis: One hundred and thirty patients with plantar fasciitis were randomized to receive ultrasound-guided interventional therapy with the use of artificial intelligence (AI) for image processing (n=65) or without AI.The outcomes of interest included pain on a Visual Analog Scale (VAS), plantar fascia thickness, elasticity, and blood flow index, AOFAS ankle function scores, and nursing satisfaction. Results revealed all... Read More »
Level 1 RCT
2%
Synopsis: 7 randomized controlled trials (RCTs) were included in this systematic review and meta-analysis comparing conservative treatment methods of intra-articular hyaluronic acid injections and corticosteroid injections.Pain scores were pooled at 2, 4, 8, 12, and 26 weeks post-injection.At early follow-up (2 weeks), treatment with corticosteroid injections resulted in lower pain when compared to treatment with hyaluronic acid injections.From 4-8 weeks, treatment displayed similar efficacy.At 12 weeks and 26 weeks, hyaluronic acid injections demonstrated significantly lower pain scores compared to corticosteroid injections. Read More »
Level 1 Meta Analysis
2%
Synopsis: Eighty-five patients with symptomatic knee osteoarthritis (OA) were randomized to receive 2 injections consisting of a single intra-articular injection of hyaluronic acid (HA) followed by platelet-rich plasma (PRP; n=43) or the single injection group consisting of PRP alone (n=42).The primary outcome of interest was pain evaluated using the Visual Analogue Scale (VAS) at 1,3, and 6-months follow-up.Secondary outcomes of interest included the following: the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and its associated subscales (pain, stiffness, and function), Lequesne index, single leg stance test (SLS), patient satisfaction, and usage of acetaminophen which all secondary outcomes were evaluated at 1, 3, and 6-months follow-up.Results of this study demonstrated that VAS was statistically significantly improved at 6-months follow-up in the combined injection group vs PRP alone (p=0.020).For secondary outcomes, WOMAC function and total scores, Lequesne Index, SLS, and patient satisfaction scores were not statistically significantly different between 2 groups at all timepoints (p>0.05).However, WOMAC pain and stiffness were both statistically significantly higher in the combined injection group vs PRP alone at 1-month follow-up (p=0.025, p=0.011; respectively). Furthermore, the consumption... Read More »
Level 1 RCT
2%
Synopsis: Eighty patients with full thickness rotator cuff tears scheduled to undergo an arthroscopic rotator cuff repair were randomized to receive an injection of atelocollagen plus hyaluronic acid (n=28), hyaluronic acid only (n=26) or no injection (n=26) after the completion of the rotator cuff repair.Outcomes of interest included pain and function on a Visual Analog Scale (VAS), the American Shoulder and Elbow Surgeons (ASES) score, range of motion (forward elevation; external rotation on the side; internal rotation at the back; abduction), the rate of retear, and the number of steroid injections.Clinical outcomes were assessed at 3, 6 and 12 months post-operation.Results revealed no significant differences in all outcomes among the three groups. However, the rate... Read More »
Level 1 RCT