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You are viewing the most viewed ACE Reports by Orthopaedic Resident/Interns over the last 30 days in all specialties.
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①
Synopsis:
12,211 patients from 21 trauma centers in the United States and Canada were included in this non-inferiority randomized trial comparing aspirin (n=6,101) and low molecular-weight heparin (n=6110).The primary outcome of interest was death by any cause at 90 days.Secondary outcomes of interest included the risk of thromboembolic events (pulmonary embolism; deep-vein thrombosis), cause-specific death, bleeding & wound complications, and the rate of infection.Aspirin was found to be non-inferior to low molecular-weight heparin with respect to the primary outcome of death by any cause. No differences in...
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Level 1 RCT
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Synopsis:
170/321 (53%) patients with distal tibial fractures from the FixDT trial consented to participate in the 5-year follow-up study comparing intramedullary nailing (n=83) and locking plate fixation (n=87).The primary outcome of interest was the Disability Rating Index (DRI).The secondary outcomes included health-related quality of life, measured with the EQ-5D-3L and EQ-VAS scales, as well as the incidence of complications.Follow-up was conducted up to 5 years post-operation.No significant differences between the two groups were observed in all outcomes, suggesting comparable efficacy and safety between the two treatment methods over 5 years. However, the significant...
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Author verified Level 1 RCT
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Synopsis:
Two hundred eighteen patients with non-displaced femoral neck fractures in elderly individuals were randomized to receive internal fixation using either percutaneous compression plate (PCCP; n=97 analyzed) or parallel screws (PS; n=97 analyzed).The primary outcome of interest was the time to full weight-bearing, with secondary outcomes including operative time, intraoperative blood loss, hemoglobin level drop, postoperative hospital stay, reduction quality, fracture healing time, Harris hip score, and postoperative complications.Outcomes were assessed at 6 weeks, 3 months, 6 months, 9 months, and 1 year after surgery. The study reveals...
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Level 1 RCT
Synopsis:
This abstract presents the 5-year follow-up results of a previously published prospective randomized controlled trial.30 patients with an International Cartilage Repair Society (ICRS) grade 3 to 4 chondral defect in the knee were randomized to receive costal chondrocyte–derived pellet-type autologous chondrocyte implantation (CCP-ACI; n=20) or microfracture (MFx; n=10).25 of these patients were followed-up at 5 years.Outcomes of interest included the Lysholm score, International Knee Documentation Committee (IKDC) score, Knee Injury and Osteoarthritis Outcome Score (KOOS), Visual Analog Scale (VAS) pain score, Magnetic resonance Observation of Cartilage Repair Tissue (MOCART) score, and treatment failure, all assessed at 5 years.In the CCP-ACI group, MOCART, Lysholm and KOOS scores improved significantly from baseline compared the the MFx group. One treatment failure...
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Conference Report
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Synopsis:
One hundred and seventy-seven patients with chronic knee pain from knee osteoarthritis (OA) were randomized to receive cooled radiofrequency ablation (CRFA; n=89) of the genicular nerves or a single intra-articular hyaluronic acid (HA; n=88).The primary outcome of interest was the number of patients who reported a =>50% reduction in pain scores from baseline after 6 months.Additional outcomes of interest included pain scores on a Numeric Rating Scale (NRS), the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index, WOMAC pain scores, WOMAC physical function scores, WOMAC stiffness scores, patient perception of treatment effect as reflected by the Global Perceived Effect (GPE) score, the Euro-Qol-5 Dimensions-5 Level (EQ-5D-5L) quality of life questionnaire, and the incidence of treatment-related and non-treatment related adverse events.Outcomes were assessed at 1, 3, and 6 months post-treatment.Results revealed a statistically significantly higher proportion of patients in the CRFA group who reported =>50% improvement in pain scores from baseline compared to the HA group (71% vs.38%, p<0.0001).NRS pain scores, WOMAC total scores, WOMAC pain scores WOMAC physical function scores, GPE scores, and EQ-5D-5L scores were statistically significantly in favour of the CRFA group at all time points compared to the HA group (p<0.05 for all).WOMAC stiffness scores were statistically significantly in favour of the CRFA group at 3 months (p=0.0022) and 6 months (p<0.0001) post-treatment. The incidence of...
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Author verified Level 1 RCT
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Synopsis:
Sixty patients undergoing unilateral primary TKA were randomized to receive surgery with a handheld semi-active robot (n=32) or a control group without robotic assistance (n=28).The primary outcomes of interest were postoperative mechanical alignment, joint line deviation and prosthesis rotation.The robotic group demonstrated improved overall mechanical alignment and reduced joint line deviation compared to the control group. No differences in...
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Level 1 RCT
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Synopsis:
14 randomized controlled trials (860 patients) comparing vibration therapy against control in patients with chronic low back pain were included in this systematic review and meta-analysis.Outcomes of interest included pain on a Normalized Pain Scale, Oswestry Disability Index (ODI), and Roland-Morris Disability Questionnaire (RMDQ).A subgroup analysis was also conducted to assess the different types of vibrational therapy used in the included studies (whole-body vibration and local vibration).All outcomes favored the vibration therapy group except for the subgroup analysis ODI scores of local vibrational therapy which was similar between the two groups. The results of...
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Level 1 Meta Analysis
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Synopsis:
64 patients with primary frozen shoulder (adhesive capsulitis) were randomized to receive either a multisite (rotator interval, intraarticular, and subacromial bursa) triamcinolone injection (MCI; n=32) or a single-site triamcinolone injection (SRI; n=32).The primary outcomes of interest include range of motion in shoulder flexion, abduction, external and internal rotation and pain on a Visual Analog Scale (VAS).Secondary outcomes included patient satisfaction, American Shoudler and Elbow Surgeons (ASES) scores, Contant-Murley Score (CMS), and the incidence of palpitations.Range of motion in flexion, abduction, internal rotation at 8 weeks, ASES scores, CMS scores, and VAS pain at 4 & 8 weeks were all significantly better in the MCI group compared to the SRI group. All other outcomes...
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Level 1 RCT
①
Synopsis:
Fifteen studies involving a total of 353,169 patients undergoing knee or hip arthroplasty were included in this meta-analysis.Among them, 156,405 patients received Spinal Anaesthesia (SA), while 196,764 patients underwent General Anaesthesia (GA).The primary outcome assessed was the incidence of Postoperative Surgical Site Infections (SSIs).Outcomes were evaluated up to 30 days post-surgery. This meta-analysis reveals...
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Level 1 Meta Analysis
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Synopsis:
47 patients with combined anterior cruciate ligament (ACL) and medial collateral ligament (MCL) injuries were randomized to receive either operative treatment on both ACL and MCL or operative treatment just on ACL. It was observed that the non-operative treatment of the MCL led to a greater range of motion and recovery of quadriceps power generation during early follow-ups.
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Author verified Level 2 RCT