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Synopsis: 182/230 patients from the PATH-2 trial responded to this 2-year follow-up study of the PATH-2 trial comparing platelet-rich plasma (PRP; n=88/114) and placebo (92/116).The outcomes of interest included the Achilles Tendon Rupture Score (ATRS), the Patient-Specific Functional Scale (PSFS), and the Short-Form 12 (SF-12) mental and physical component quality of life scores. The results of... Read More »
Level 1 RCT
20%
Synopsis: 340 primary total knee arthroplasties were performed with cementless fixation of the femoral component and cement fixation of the patellar and tibial components.The knees were randomized to receive cefuroxime-impregnated cement or cement without cefuroxime.Patients were followed-up for an average of 49 months. The rate of... Read More »
Level 2 RCT
20%
Synopsis: Thirty-six patients with knee osteoarthritis were randomized to receive additional extracorporeal shockwave therapy (n=18) or no additional therapy (n=18) in combination with a 3 week physical therapy program consisting of transcutaneous electrical nerve stimulation, magnetic field therapy, and quadriceps strength training.Outcomes of interest included the change from baseline in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), pain on a Visual Analog Scale (VAS), and the 6-minute walk test.Outcomes were assessed after 3 weeks of treatment and 1 week after treatment was completed. Results revealed significantly... Read More »
Level 1 RCT
20%
Synopsis: 122 patients undergoing intertrochanteric fracture surgery were randomized to receive two doses of 1g tranexamic acid delivered intravenously prior and after surgery (n=61) or placebo (n=61).The primary outcome of interest was hidden blood loss.Secondary outcomes of interest included intraoperative and total blood loss, hemoglobin levels and drop, transfusion rate, and the incidence of complications.Results demonstrated that intravenous tranexamic acid significantly reduced hidden, total and intraoperative blood loss, hemoglobin drop, and the need for transfusion, with no increase in the rate of 90-day complications vs. Read More »
Level 1 RCT
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