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57%
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14%
Synopsis: 40 patients with rotator cuff tendinitis were randomized to subacromial injection of either platelet-rich plasma or triamicinolone acetonide.Patients were assessed for pain and functional score over a 12-month follow-up.Change in Constant score after 12 months was significantly greater in the PRP group compared to the steroid group. Both groups demonstrate... Read More »
Conference Report
12%
Synopsis: Eight randomized controlled trials were included in this meta-analysis comparing the results of intra-articular steroid injection to either sham injection or no injection in the treatment of frozen shoulder.Results were pooled at 4-6 weeks, 12-16 weeks, and 24-26 weeks.Pain scores were significantly lower following IA steroid injection versus control at all three time intervals.Shoulder range of motion was also reported to be greater following IA steroid injection versus control. Results from clinical... Read More »
Conference Report
8%
Synopsis: 126 patients with frozen shoulder were randomized to dual glenohumeral and subacromial injection of betamethasone once per week for 5 weeks, to glenohumeral injection alone once per week for 5 weeks, or to oral non-steroidal anti-inflammatory drugs (NSAIDs) for 5 weeks.Patients were assessed for pain, function, and range of motion over the first 6 months post-treatment.Results demonstrated significantly lower pain in the injection group compared to the oral NSAIDs group. Function and range... Read More »
Conference Report
8%
Synopsis: 44 patients with a small (<1.0cm), partial-thickness, interstitial tear of the supraspinatus tendon were allocated to a standardized physical therapy program and randomized to treatment with or without the addition of three platelet rich plasma injections.Patients were followed-up at 3 and 6 months on the Shoulder Pain and Disability Index.At 6 months, SPADI scores were significantly lower in the PRP group compared to the control group. No treatment-related adverse... Read More »
Conference Report
5%
Synopsis: 142 knees, in 84 patients, with moderate severity osteoarthritis were randomized to intraarticular injection of either platelet-rich plasma or hyaluronic acid.Patients were assessed over 12- and 24-week follow-up for results on the Knee Society Score and a visual analog scale for pain. While the HA... Read More »
Conference Report
4%
Synopsis: 70 recreationally-active patients with anterior cruciate ligament (ACL) tear were randomized to either immediate reconstruction (within 8 days) or delayed reconstruction (6-10 weeks after injury).Patients were assessed for total sick leave days over the first year after injury. The mean number... Read More »
Conference Report
3%
Synopsis: 40 patients scheduled for total knee arthroplasty were randomized to either receive or not receive platelet-rich plasma application during surgery.Patients were assessed for hemoglobin and hematocrit levels over the first 48 hours after surgery, and functional and pain outcomes over the first 2 months after surgery.Results demonstrated no significant differences in Hb level, Hct level, knee range of motion, or scores on the Western Ontario and McMaster Universities Osteoarthritis Index between groups. Pain scores were... Read More »
Conference Report
3%
Synopsis: 99 middle-aged patients were randomized to compare an exercise program alone to arthroscopic partial meniscectomy plus a postoperative exercise program in the treatment of degenerative medial meniscus tears.The exercise program was completed over 8 weeks, with outcomes in pain and function being assessed at the completion of the program, and again at 6 months. The results indicated... Read More »
Author verified Level 2 RCT
2%
Synopsis: Six ACE Reports (5 randomized controlled trials and 1 systematic review/meta-analysis) were identified from the OrthoEvidence database which evaluated the efficacy of platelet-rich plasma in the treatment of knee osteoarthritis.All included studies were randomized controlled trials, and reported clinical and functional assessment at various time points between 1 and 6 months following treatment.Pooled analysis of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Total scores suggested a possible beneficial effect with PRP injection in comparison to saline and a lower effect versus hyaluronic acid.Beneficial effects were also noted for individual subscales of the WOMAC assessment (pain, stiffness, and physical function).However, pooling of OMERACT-OARSI responders and a review of the literature indicated that there was no significant difference between PRP and comparison groups in other functional outcome measures, such as the International Knee Documentation Committee (IKDC) assessment and Knee Injury and Osteoarthritis Outcome Score (KOOS).Furthermore, contrasting results were obtained between two studies reporting function on the Lequesne Index. The discrepancy in... Read More »
ACE Review
2%
Synopsis: 72 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized to daily sessions of high-intensity laser therapy (HILT) for 1 week, or to a sham intervention.Patients were followed up for pain at rest, on palpation, and on movement, pressure-pain threshold, the maximum pressure under the heel during static stance, the maximum pressure under the heel during dynamic walking, and the total plantar surface of each leg. Percent changes from... Read More »
Level 2 RCT