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24%
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17%
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100%
6%
Synopsis: 196 patients were randomized to receive either hyaluronic acid (HA) or a placebo in knee osteoarthritis (OA) treatment.HA was compared to placebo to test the efficacy in reduction of pain and function.Results of this study found no significant benefit of HA treatment over placebo for visual analogue score, Western Ontario and McMaster Universities Arthritis Index (WOMAC), or knee flexion.However, both groups demonstrated significant improvement from baseline values to 6 month follow-up. Read More »
Level 2 RCT
4%
Synopsis: 39 patients with a lesion of the supraspinatus tendon were randomized to receive either platelet-rich plasma (PRP) injections or dry needling to determine the comparative efficacy of the treatments for rotator cuff pathology.Follow-up was conducted for 6 months following the second injection, which took place 4 weeks after the first injection.Analysis at final follow-up indicated that total score on the Shoulder Pain and Disability Index was significantly better in the PRP group; however significance did not remain when pain and disability subscales were assessed individually. Improvement in range... Read More »
Author verified Level 2 RCT
4%
Synopsis: 60 patients with shoulder impingement syndrome were randomized to receive a dual-target (long head of bicep tendon and subacromial bursa) subacromial corticosteroid injection or a standard subacromial corticosteroid injection for the relief of pain and improvement of functional outcomes.The primary outcomes of interest were the Shoulder Pain and Disability Index (SPADI) pain, function and total scores.Secondary outcomes of interest included pain at rest, during the night, and during overhead activities.Follow up was performed at 1 and 3 months post-injection.Results found no significant differences in the improvement of all outcomes from baseline at 1 month post-injection between the two groups. However, the improvement... Read More »
Level 1 RCT
3%
Synopsis: 40 patients, greater than 18 years of age, with primary trigger finger were randomized into one of two treatment groups to receive different steroid injection techniques to see the overall effectiveness of each.Patients in one group received injection through the conventional technique (over the metacarpal head), while those in the second group received an injection using the midproximal phalanx technique. Results showed that... Read More »
Level 2 RCT
3%
Synopsis: 81 patients diagnosed with adhesive capsulitis of the shoulder were randomized to receive either hypertonic saline solution or regular saline in capsule-preserving intra-articular hydraulic distension.The purpose of the study was to determine the functional and pain and disability effects of hypertonic saline 2 weeks after surgery. Results indicated significant... Read More »
Level 2 RCT
2%
Synopsis: 36 patients with tibiofemoral osteoarthritis were randomized into three groups to assess the efficacy and compare transcutaneous electrical nerve stimulation in combination with therapeutic exercise to a placebo and control group.TENS treatment has been proposed to improve muscle activation which could provide benefits for this population which often suffers from quadriceps activation failure. The results from... Read More »
Level 2 RCT
2%
Synopsis: Seventy-four patients with mild trigger finger were randomized to undergo either physiotherapy or receive corticosteroid injections, to determine which of the two conservative treatments was more effective.At 3 months the success rate was 97.4% for patients treated with corticosteroid injection and 68.6% for patients treated with physiotherapy.The patients with success at 3 months had an additional follow-up at 6 months following treatment to measure recurrence.At the 6 month period assessment results revealed that patients who received corticosteroid injections had better pain scores, higher satisfaction rate, and stronger grip strength.However, patients that received physiotherapy treatment had no recurrence of pain or triggering. Thus physiotherapy may... Read More »
Author verified Level 2 RCT
2%
Synopsis: Six ACE Reports (5 randomized controlled trials and 1 systematic review/meta-analysis) were identified from the OrthoEvidence database which evaluated the efficacy of platelet-rich plasma in the treatment of knee osteoarthritis.All included studies were randomized controlled trials, and reported clinical and functional assessment at various time points between 1 and 6 months following treatment.Pooled analysis of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Total scores suggested a possible beneficial effect with PRP injection in comparison to saline and a lower effect versus hyaluronic acid.Beneficial effects were also noted for individual subscales of the WOMAC assessment (pain, stiffness, and physical function).However, pooling of OMERACT-OARSI responders and a review of the literature indicated that there was no significant difference between PRP and comparison groups in other functional outcome measures, such as the International Knee Documentation Committee (IKDC) assessment and Knee Injury and Osteoarthritis Outcome Score (KOOS).Furthermore, contrasting results were obtained between two studies reporting function on the Lequesne Index. The discrepancy in... Read More »
ACE Review
2%
Synopsis: 52 patients with grade IV knee osteoarthritis were randomly assigned to receive intra-articular injection of either hyaluronan (HA) or saline placebo.The purpose of this study was to determine if intra-articular HA, administered in two courses of 5 weekly injections, could delay the need for joint replacement surgery.Results demonstrated no significant difference in the time to joint replacement between the two groups. Clinical outcome, measured... Read More »
Author verified Level 2 RCT
2%
Synopsis: 126 patients with idiopathic adhesive capsultitis were randomized to intra-articular glenohumeral corticosteroid injection, subacromial corticosteroid injection, or a combination of both intra-articular and subacromial corticosteroid injection.The purpose of this study was to determine if a combined injection strategy offered better patient-reported clinical outcomes when compared to intra-articular injection alone or subacromial injection alone. American Shoulder and... Read More »
Level 2 RCT