To focus on specific sub specialties check/uncheck boxes on left
28%
22%
20%
8%
6%
5%
4%
3%
2%
1%
1%
Displaying
100%
7%
Synopsis: 1583 patients with symptomatic knee osteoarthritis were randomized to either glucosamine monotherapy, chondroitin monotherapy, combined glucosamine and chondroitin therapy, celecoxib 200mg daily, or placebo.Patients were assessed over 24 weeks of treatment.In the primary analysis, only the celecoxib group demonstrated a significantly higher rate of patients attaining the primary efficacy endpoint - a reduction of WOMAC pain by a minimum of 20% relative to baseline - compared to placebo. However, when only... Read More »
RCT
6%
Synopsis: 348 patients with femoroacetabular impingement syndrome were randomized to either arthroscopic intervention or a personal hip therapy programme.Patients were assessed after 6 and 12 months (primary endpoint) using the International Hip Outcome Tool (iHOT-33; primary outcome), the EQ-5D-5L and VAS, and the SF-12 measures, and were monitored for any adverse events. A cost-utility analysis was performed using quality-adjusted life-years generated from results on the EQ-5D-5L.Results demonstrated significantly greater iHOT-33 scores at 12 months in the arthroscopy group compared to the personalized hip therapy group, and the difference exceeded the minimum clinically important difference (MCID) threshold.Secondary outcome measures did not significantly differ between groups. The cost-effectiveness of... Read More »
Level 2 RCT
4%
Synopsis: 180 patients scheduled for arthroscopic rotator cuff repair were randomized to postoperative analgesia for 2 weeks using either celecoxib 200mg, ibuprofen 385mg, or tramadol 50mg.Primary study variables included pain scores and rescue analgesia consumption over the first 2 weeks.Secondary study variables, implemented a posteriori, were pain scores, functional scores, and tendon healing on the Sugaya classifications over a 24-month follow-up.Primary study variables demonstrated no significant differences between groups.Secondary study variables also demonstrated no significant differences between groups, with the exception of retear rate. Retear rate was... Read More »
Level 1 RCT
4%
Synopsis: 390 novice distance runners were randomized to 2 weeks of either a gait re-training program on an instrumented treadmill with real-time visual feedback or control intervention of simple treadmill running.Outcomes recorded included vertical average loading rate (VALR) and vertical instantaneous loading rate (VILR) while running at 8km/h and 12km/h.Runners were also assessed for the incidence of running-related injury over the following 12 months after the intervention period.Results demonstrated significantly lower VALR and VILR at both 8km/h and 12km/h paces in the gait re-training group compared to the control group. The overall incidence... Read More »
Level 2 RCT
4%
Synopsis: Six randomized controlled trials were included in this meta-analysis evaluating the efficacy of platelet-rich plasma injections for the treatment of acute muscle injuries.Among all studies, time to return to sport was significantly shorter following PRP injection versus control treatment. In contrast, in... Read More »
Level 1 Meta Analysis
3%
Synopsis: 80 patients with grade 2-3 gluteal tendinopathy were randomized to intratendinous injection of either platelet-rich plasma or corticosteroid (betamethasone).Patients were assessed over a 12-week follow-up for results on the modified Harris Hip Score.Results at 12 weeks demonstrated significantly higher scores on the mHHS in the PRP group compared to the CS group. Additionally, the rate... Read More »
Author verified Level 1 RCT
3%
Synopsis: 60 patients with lateral epicondylitis were randomized to an injection into the extensor carpi radialis brevis (ECRB) of either botulinum toxin type A (BoNT-A) or placebo.Patients were assessed after 30 and 90 days.The primary outcome was the rate of patients who experienced a minimum 50% reduction in pain on a visual analog scale.Additional outcomes investigated included the rate of patients who experienced interference with daily activities, sporting events, and professional activities, the incidence of side effects, and the rate of patients who requested additional treatment after 90 days was documented.Results demonstrated a significantly higher rate of patients in the BoNT group compared to the placebo group who experienced 50% or more reduction in pain after 90 days.Other outcomes which significantly favoured the BoNT-A group were interference with daily activities or rate of request for subsequent treatment. The rate of... Read More »
Author verified Level 1 RCT
3%
Synopsis: Four studies - three randomized trials and one nonrandomized trial - which investigated the effect of the addition of taping to physiotherapy versus physiotherapy alone in the treatment of subacromial impingement were included in this systematic review.Due to clinical heterogeneity, a meta-analysis was unable to be performed.For most outcome measures, including pain at rest, pain on movement, patient-reported disability, and range of motion, there was at least one study which provided data in support of taping versus control. Nonetheless, there was... Read More »
Author verified Level 2 Meta Analysis
3%
Synopsis: 8 randomized controlled trials were included in this systematic review to determine the effect of balance and proprioceptive training on outcomes following total knee and hip arthroplasty.Both studies that assessed preoperative and postoperative training programs were included.The results of this meta-analysis indicated that prehabilitation with balance and proprioception training exercises in total knee and total hip arthroplasty had little impact on the improvement of postoperative outcomes. In contrast, postoperative... Read More »
Level 2 Meta Analysis
2%
Synopsis: 165 patients scheduled for total hip arthroplasty were randomized to one of three groups for postoperative analgesia: periarticular infiltration with ropivacaine (PAI-R), periarticular infiltration with liposomal bupivacaine (PAI-L), or peripheral nerve block (PNB) via a continuous lumbar plexus block.The primary outcome was maximum pain severity experienced during the morning of postoperative day 1. Results demonstrated statistically... Read More »
Level 2 RCT