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5%
Synopsis: Six hundred and forty-four patients with knee osteoarthritis (OA) were randomized to receive either platelet-rich plasma (PRP; n=322) or sham saline solution (n=322).Outcomes of interest were the Western and McMaster Universities Osteoarthritis Index (WOMAC) pain, stiffness, function subscales and an overall score, International Knee Documentation Committee (IKDC) score, Visual Analog Scale pain, and levels of tumor necrosis factor-alpha (TNF-a), interleukin-1B (IL-1B), and cartilage volume. The PRP group... Read More »
Level 1 RCT
5%
Synopsis: Sixty patients (>45 years) with knee osteoarthritis were randomized to receive rectus femoris stretching exercises in addition to a 4-week lower body stretching and strengthening exercise program (n=30) or the 4-week program alone (n=30).The outcomes of interest included pain on a Visual Analog Scale (VAS), Western Ontario and McMaster Universities (WOMAC) osteoarthritis index, range of motion, and gait parameters (step length, speed).Outcomes were assessed before and after treatment.The results demonstrated significantly better WOMAC scores, better flexion range of motion and pain scores on both sides, and superior gait parameters in the rectus femoris stretching group. Stretching the rectus... Read More »
Level 1 RCT
5%
Synopsis: Forty- four patients with rotator cuff tendinopathies were randomized to receive a single subacromial injection of corticosteroid (n=22) or three weekly subacromial injections of ozone (n=22).The primary outcome measure was the Western Ontario Rotator Cuff (WORC) score.Secondary outcome measures include the Shoulder Pain and Disability Index (SPADI) and pain on a Visual Analog Scale (VAS).Outcomes were assessed at 4 and 12 weeks follow-up.Both groups demonstrated significant improvements from baseline in all outcomes. However, the clinical... Read More »
Level 1 RCT
3%
Synopsis: A meta-analysis of 28 randomized controlled trials was conducted to compare the safety, efficacy, and durability of acupuncture therapy for sciatica.The total effective rate, pain measured using the Visual Analog Scale (VAS), and pressure pain threshold were measured. All three outcomes... Read More »
Level 1 Meta Analysis
3%
Synopsis: Seventy-one patients with hip osteoarthritis were randomized to receive conventional therapy with either continuous ultrasound (n=21), pulsed-mode ultrasound (n=17), ultrasound and transcutaneous electrical nerve stimulation (n=15), or sham ultrasound (n=18).Outcomes such as Visual Analog Pain (VAS) pain scores at rest, 6-minute walk test, Western Ontario and McMaster Universities (WOMAC) index, short-form-36 (SF-36), and patient global impression of change (PGIC) were assessed at 2 and 14 weeks. No significant differences... Read More »
Level 1 RCT
3%
Synopsis: Twenty-six patients with supraspinatus tendinitis were randomized to receive either extracorporeal shock wave therapy (ESWT; n=13) or ultrasound-guided injection therapy (US; n=13).Outcomes of interest were pain measured using the Visual Analog Scale (VAS), and function measured using the Constant Shoulder Score and the American Shoulder and Elbow Surgeons (ASES) score. No differences were... Read More »
Level 1 RCT
3%
Synopsis: One hundred and thirty-six patients with secondary frozen shoulder were randomized to receive manipulation under anesthesia (n=68) or celecoxib (n=68), both in addition to an exercise program.The primary outcome of interest was shoulder function as measured by the Constant-Murley Score.Secondary outcomes of interest included the McGill Pain Questionnaire containing Pain Rating Index and Pressure Pain Intensity, and range of motion.Outcomes were measured up to 12 weeks follow-up.Constant-Murley scores were significantly in favour of the manipulation group at 1 day, 2 weeks, 4 weeks, and 12 weeks follow-up.Range of motion and Pressure Pain Intensity were also significantly in favour of the manipulation group at all time points. Pain Rating Index... Read More »
Level 1 RCT
2%
Synopsis: Five studies involving 339 patients with carpal tunnel syndrome were included in this systematic review and meta-analysis comparing distal and proximal approaches to corticosteroid injection.Pooled outcomes of interest included the Boston Carpal Tunnel Questionnaire (BCTQ), pain on a Visual Analog Scale (VAS), electrophysiological outcomes, pain on injection, duration of injection, and adverse events.Results revealed no differences in pooled BCTQ function or symptom scores between the two approaches.No difference in pain intensity or the risk of adverse events was observed either.However, a distal approach was found to take significantly less time to perform and resulted in a better sensory nerve action potential amplitude vs. Read More »
Level 1 Meta Analysis
2%
Synopsis: 371 patients with mid-portion Achilles tendinopathy were included in this systematic review and meta-analysis comparing eccentric exercise to control (other forms of exercise, electrotherapies, no treatment).Outcomes of interest included pain, function, range of motion, and strength.Only pain had sufficient data to pool; no difference in pooled pain scores was observed between the two groups. Future high-quality studies... Read More »
Level 1 Meta Analysis
2%
Synopsis: Sixty patients with chronic neck pain were randomized to either the dry needling arm (n=32) or the sham dry needling arm (n=28).The primary outcome of this trial was to determine the local shear wave speed and Young's modulus, and pain pressure threshold.No secondary outcomes were recorded for this study.The results of this trial showed significant differences in the control point after 10 minutes, as well as the myofascial trigger point (MTrP). No significant differences... Read More »
Level 1 RCT