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4%
Synopsis: One hundred elderly patients with unstable distal radius fractures were randomized to receive volar plating (n=50) or plaster cast immobilization (n=50).The primary outcome of interest was the complication rate after 12 months.Secondary outcomes of interest included patient-reported outcome measures (Quick-Disability of the Arm, Shoulder and Hand [Quick-DASH]; pain on a Numeric Rating Scale [NRS]; the Patient Rated Wrist/Hand Evaluation [PRWHE]), range of motion, grip strength, and the European Quality of Life 5 Dimensions 3 Levels (EQ-5D) measure.Outcomes were assessed up to 12 months follow-up.The results of this study found no significant differences in primary and secondary outcomes, with the exception of range of motion at 5 weeks and 6 months, which was in favour of the volar plating group. The results of... Read More »
Level 1 RCT
4%
Synopsis: Eleven randomized controlled trials with a total of 972 patients were included in this meta-analysis comparing early and delayed anterior cruciate ligament reconstruction.The primary outcomes of interest were functional outcomes and the risk of complications.Additional outcomes included operative time.The results of this study found no differences in pooled operative time, range of motion, knee stability, Tegner score, or retear and infection between the two groups.Lysholm scores at 1 & 2 years and IKDC scores at 6 months, however, were significantly in favour of the early reconstruction group, but were limited to 1-2 studies per timepoint in the pooled analyses. The results of... Read More »
Level 1 Meta Analysis
3%
Synopsis: 182/230 patients from the PATH-2 trial responded to this 2-year follow-up study of the PATH-2 trial comparing platelet-rich plasma (PRP; n=88/114) and placebo (92/116).The outcomes of interest included the Achilles Tendon Rupture Score (ATRS), the Patient-Specific Functional Scale (PSFS), and the Short-Form 12 (SF-12) mental and physical component quality of life scores. The results of... Read More »
Level 1 RCT
2%
Synopsis: Two hundred patients with subacromial impingement were randomized to receive the usual nonoperative care (n=100) or a large dose of shoulder strengthening in addition to usual care (n=100).The primary outcome of interest was the Shoulder Pain and Disability Index (SPADI) at 4 months follow-up.Other outcomes of interest included shoulder strength, range of motion, health-related quality of life and the Patient Acceptable Symptom State (PASS).No significant or clinically relevant between group differences were found for any outcome at 4 months follow-up. At 4 months... Read More »
Level 1 RCT
2%
Synopsis: One hundred and twenty-three patients with a rotator cuff tear were randomized to receive either a complete rotator cuff repair with a crimson duvet procedure (n=62) or complete rotator cuff repair alone (n=61).The primary outcome of this trial was to assess the nonhealing rate via MRI or ultrasonography.The secondary outcomes of this trial were to assess shoulder function (American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form (ASES) score, Constant score, and range of motion). The results of... Read More »
Level 1 RCT
2%
Synopsis: One hundred and twenty-six patients with open tibial shaft fracture were included in this 3-5 year observational follow-up study comparing intramedullary nailing (n=67) and external fixation (n=59).The primary outcome of interest was a composite of death, reoperation for deep infection, non-union, and malalignment.Unresolved complications, quality of life, radiographic alignment, and function were also assessed.The results revealed comparable rates of death and reoperation due to deep infection, non-union, and malalignment.25% of patients who reported a primary outcome event had unresolved complications (fracture-related infection or non-union).Quality of life & functional outcomes were also similar between groups.The rate of malalignment was slightly higher in the external group. Unresolved infection and... Read More »
Level 2 RCT
2%
Synopsis: Eighty-four patients undergoing unicompartmental knee arthroplasty were randomized to receive a periarticular injection performed prior to joint incision (early stage; n=42) or after implantation of the prosthesis (late stage; n=42).The primary outcome of interest was pain intensity, measured on a 100-point Visual Analog Scale (VAS).Secondary outcomes of interest included range of motion, rescue analgesia consumption, and in-hospital complications, measured up to 120 hours post-operation.The results of this study found early-stage injection to provide superior pain relief in the post-operative recovery room.However, no differences in pain intensity were observed between the two groups at 3-120 hours post-operation. No differences in... Read More »
Level 1 RCT
2%
Synopsis: 16 randomized trials with a total of 968 patients scheduled for total knee arthroplasty were included in this systematic review and meta-analysis comparing prehabilitation exercise therapy and control.The primary outcome of interest was the improvement in knee function within the first year post-operation: data was assessed pre-operation, 1 day to 4 weeks post-operation, at 3 months post-operation, and at 6-12 months post-operation.Results found that prehabilitation resulted in significantly better knee function up to 3 months post-operation. However, the quality... Read More »
Level 1 Meta Analysis
1%
Synopsis: Ninety-seven patients undergoing treatment for advanced cubital tunnel syndrome were randomized to receive either ulnar nerve decompression and transposition with supercharged end-to-side motor nerve transfer (n=47) or ulnar nerve decompression and transposition alone (n=50).The primary outcomes of this trial were to assess the predictive factors for poor recovery as well as describing the nerve transfer procedure through a small incision.The results of this trial illustrated that ulnar nerve decompression and anterior subfascial transposition with supercharged end-to-side anterior interosseous nerve-to-ulnar motor nerve transfer is superior to the standard treatment when considering pinch strength, compound muscle action potential (CMAPa) of the first dorsal interossei and abductor digiti minimi. Functional scores status... Read More »
Level 1 RCT
1%
Synopsis: Forty patients undergoing total knee arthroplasty for primary knee osteoarthritis were randomized to receive either rivaroxaban (n=20) or Aspirin (acetylsalicylic acid; n=20).Outcomes of interest were hematocrit levels, deep vein thrombosis, and adverse events.Hematocrit levels at 6 and 24 hours, and 2 weeks were similar between the two groups.The incidence of blood transfusion, bleeding, wound complications, and reoperations were also similar between the two groups. No patients presented... Read More »
Level 1 RCT