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27%
17%
16%
9%
8%
7%
4%
4%
3%
3%
2%
<1%
<1%
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100%
4%
Synopsis: 126 patients scheduled for arthroscopic rotator cuff repair were randomized to one of four shoulder skin preparation methods: a solution or 1% chlorhexidine gluconate and 70% isopropyl alcohol with or without an antibacterial adhesive drape, or a solution of povidone-iodine with or without an antibacterial adhesive drape.The purpose of this study was to determine if skin preparation with chlorhexidine plus a drape demonstrated a significantly lower rate of Propionibacterium acnes (P.acnes) suture colonization compared to the other three groups.Compared to the povidone-iodine without drape group, the chlorhexidine plus drape group demonstrated a significantly lower incidence of positive culture identification. Statistical comparisons to... Read More »
Author verified Level 2 RCT
3%
Synopsis: 60 patients scheduled for total knee arthroplasty were randomized to either uncemented fixation with hydroxyapatite-coated components, or to cement fixation.Patients were assessed for component migration via maximum total point motion using radiostereometric analysis.Results demonstrated significantly greater total MTPM after 5 years in the uncemented group compared to the cemented group, but no significant difference between groups in the change in MTPM from 1 year 5 years. Therefore, the results... Read More »
Level 2 RCT
3%
Synopsis: 136 patients scheduled for total knee arthroplasty were randomized to an ultracongruent tibial insert or a posterior-stabilized total knee implant.Patients were assessed over a 1-year follow-up.Groups did not demonstrate any significant differences in knee range of motion or function on the UCLA activity score at 1 year. Oxford Knee Scores... Read More »
Level 2 RCT
3%
Synopsis: 348 patients with femoroacetabular impingement syndrome were randomized to either arthroscopic intervention or a personal hip therapy programme.Patients were assessed after 6 and 12 months (primary endpoint) using the International Hip Outcome Tool (iHOT-33; primary outcome), the EQ-5D-5L and VAS, and the SF-12 measures, and were monitored for any adverse events. A cost-utility analysis was performed using quality-adjusted life-years generated from results on the EQ-5D-5L.Results demonstrated significantly greater iHOT-33 scores at 12 months in the arthroscopy group compared to the personalized hip therapy group, and the difference exceeded the minimum clinically important difference (MCID) threshold.Secondary outcome measures did not significantly differ between groups. The cost-effectiveness of... Read More »
Level 2 RCT
3%
Synopsis: 1583 patients with symptomatic knee osteoarthritis were randomized to either glucosamine monotherapy, chondroitin monotherapy, combined glucosamine and chondroitin therapy, celecoxib 200mg daily, or placebo.Patients were assessed over 24 weeks of treatment.In the primary analysis, only the celecoxib group demonstrated a significantly higher rate of patients attaining the primary efficacy endpoint - a reduction of WOMAC pain by a minimum of 20% relative to baseline - compared to placebo. However, when only... Read More »
RCT
2%
Synopsis: 180 patients scheduled for arthroscopic rotator cuff repair were randomized to postoperative analgesia for 2 weeks using either celecoxib 200mg, ibuprofen 385mg, or tramadol 50mg.Primary study variables included pain scores and rescue analgesia consumption over the first 2 weeks.Secondary study variables, implemented a posteriori, were pain scores, functional scores, and tendon healing on the Sugaya classifications over a 24-month follow-up.Primary study variables demonstrated no significant differences between groups.Secondary study variables also demonstrated no significant differences between groups, with the exception of retear rate. Retear rate was... Read More »
Level 1 RCT
2%
Synopsis: A total of 8 randomized controlled trials were included for data on efficacy, and 9 randomized controlled trials were included for data on harms, in this meta-analysis which investigated the effects of vitamin D and/or calcium supplementation in community-dwelling adults over the age of 50 years.Overall, quantitative and qualitative assessment of fractures rates from efficacy studies demonstrated no significant differences between vitamin D alone, calcium alone, and vitamin D plus calcium compared to placebo. In the harms... Read More »
Author verified Level 1 Meta Analysis
2%
Synopsis: 97 patients with an acute syndesmotic injury were randomized to surgical stabilization with either a suture button device or a syndesmotic screw.Patients were followed-up for results on function, pain, and radiological outcome over a 2-year follow-up.Results demonstrated that the suture button device was significantly favoured over a syndesmotic screw for functional outcome from 6 months to 2 years, for dynamic pain scores from 1 year to 2 years, and the rate of malreduction (ie. loss of reduction... Read More »
Author verified Level 2 RCT
2%
Synopsis: 109 patients scheduled for total knee arthroplasty were randomized to surgery with either the use of patient-specific cutting guides or conventional intra- and extramedullary guides.Patients were assessed for overall lower limb alignment, femoral component alignment in the coronal, sagittal, and axial planes, tibial component alignment in the coronal and sagittal planes, and patient-reported outcome measures and knee range of motion over a 2-year follow-up. Results demonstrated no... Read More »
Level 2 RCT
1%
Synopsis: Four studies were included in this meta-analysis comparing outcomes after intracapsular hip fracture fixation between a dynamic locking plate or alternative implants, including sliding hip screws and multiple cannulated cancellous screws.The dynamic locking plate implant of interest was the Targon FN plate (Aesculap). Pooled analyses demonstrated... Read More »
Level 2 Meta Analysis