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Synopsis: One hundred and seven patients with medial compartment osteoarthritis were randomized to receive unicompartmental knee arthroplasty (UKA; n=57) or total knee arthroplasty (TKA; n=50).The primary outcomes of this trial were to assess patient-reported outcomes such as Knee Injury and Osteoarthritis Outcome Score, Joint Replacement (KOOS, JR), Knee Society Score (KSS), Forgotten Joint Score (FJS), range of motion (ROM), and VR-12 global health scores at 6 weeks and 6 months follow-up.Radiographic and surgical complications were also recorded.The results of this trial showed no significant differences in KOOS, JR, KSS, and FJS at 6 weeks and 6 months follow-up. Significant differences were... Read More »
Level 1 RCT
4%
Synopsis: Seventy-two patients with end-stage knee osteoarthritis were randomized to receive either robot-assisted total knee arthroplasty (RA-TKA; n=37) or conventional manual total knee arthroplasty (CM-TKA; n=35).Outcomes that were assessed in this trial were functional outcomes such as knee flexion-extension range of motion (ROM), American Knee Society Score (KSS), and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at 90 days post-op.Radiological outcomes were also assessed at 90 days of follow-up.Functional outcomes (KSS, WOMAC, & ROM) were similar between the two groups at 90 days. Significant differences in... Read More »
Level 1 RCT
4%
Synopsis: Ninety patients with displaced, operative clavicle fractures were randomized to receive fixation utilizing a locking plate (n=45) or nonlocking plate (n=45).The outcomes of interest were complication rates, union rates and functional outcomes measured using the Constant score.There were no differences in overall complication rates between groups.The locking plate group had a significantly faster time to radiographic union and significantly lower rate of delayed union. No difference in... Read More »
Level 1 RCT
4%
Synopsis: 316 patients with non-acute anterior cruciate ligament (ACL) injuries and persistent instability were randomized to receive immediate surgery (n=156) or rehabilitation (n=160).The primary outcome of interest was the Knee Injury and Osteoarthritis Outcome Score - 4 domain (KOOS4).Secondary outcomes of interest included quality of life measures, the Tegner activity score, resource use, complications and patient satisfaction.Primary follow-up occurred at 18 months.The results of this study found that, whilst both groups showed improvement, patients who received immediate surgery had significantly better knee function, pain, patient satisfaction, and Tegner activity scores compared to the rehabilitation group.Surgery was found to have a 72% chance of being cost-effective vs. Read More »
Author verified Level 1 RCT
3%
Synopsis: One hundred and ninety seven patients who underwent operative fixation of an ankle syndesmotic injury were randomized to receive routine removal (n=93) or on-demand removal (104) of their syndesmotic screw after surgery.The primary outcome was function as measured by the Olerud-Molander Ankle Score (OMAS). Secondary outcomes of... Read More »
Level 1 RCT
3%
Synopsis: Forty-seven patients with anterior cruciate ligament (ACL) tears with or without meniscal injury were randomized to receive an arthroscopic ACL reconstruction with femoral side graft fixation using an adjustable-length loop device (n=24) or a fixed-length loop device (n=23).The outcomes of interest included knee function on the International Knee Documentation Committee (IKDC) and Lysholm scoring systems, knee stability via the Lachman and pivot shift tests, and quadriceps wasting measured by thigh circumference.Outcomes were assessed at 2 years post-operation. No significant differences... Read More »
Level 1 RCT
3%
Synopsis: Twenty-six patients with sacroiliac joint pain were randomized to either the corticosteroid injection group (n=11) or the intra-articular platelet-rich plasma injection (PRP; n=15) group.The two primary outcomes of this trial were pain on the numeric pain rating scale (NPRS) and functional disability using the Oswestry Low Back Pain Disability Questionnaire (ODI), measured at 1, 3, and 6 months. Significant differences were... Read More »
Level 1 RCT
2%
Synopsis: Eleven randomized controlled trials evaluating either leukocyte-rich platelet-rich plasma (LR-PRP) or leukocyte-poor platelet-rich plasma (LR-PRP) compared to control injections in patients with lateral epicondylitis.The outcomes of interest were pain scores and clinical effectiveness.The LP-PRP group demonstrated no significant improvements in pain scores compared to control injections.The LR-PRP group demonstrated significantly greater reductions in pain compared to the control group at long-term follow-up.There was no difference in the proportion of patients who achieved treatment success in the LP-PRP group compared to the control group. However, patients who... Read More »
Level 1 Meta Analysis
2%
Synopsis: A meta-analysis of six randomized controlled trials comparing the effect of early administration of bisphosphonate therapy or control (delayed) administration of bisphosphonates on time to fracture healing was conducted.Outcomes of interest were time to fracture healing, rates of delayed union, non-union, and revision surgery.The mean time to fracture healing was shorter in patients who received early bisphosphonate therapy compared with the placebo group. No significant differences... Read More »
Level 1 Meta Analysis
2%
Synopsis: Eighty-eight patients with first metatarsophalangeal (MTP) joint osteoarthritis were randomized to receive contoured foot orthoses (n=47) or sham insoles (n=41).The primary outcomes of this trial were pain scores in the first MTP during the last week of follow-up using a numerical rating scale (NRS).Secondary outcomes such as pain and function were assessed using the Foot Health Status Questionnaire (FSHQ) and overall average pain using the Numeric Rating Scale (NRS), and quality of life using the Assessment of Quality of Life instrument.Physical activity was also assessed at 12 weeks using the Physical Activity Scale for the Elderly. No significant differences... Read More »
Level 1 RCT