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Synopsis: 16 randomized controlled trials assessing operative versus nonoperative management for distal radius fractures were included in this systematic review and meta-analysis.The primary outcome of interest was Patient-Rated Wrist Evaluation (PRWE) at 12 months.Secondary outcomes of interest included Disabilities of the Arm, Shoulder, and Hand (DASH) score, grip strength, complications, and radiographic outcomes. Both PRWE and... Read More »
Conference Report
3%
Synopsis: 843 patients were included in this study consisting of a randomized trial (n=555) and natural experiment (n=288), aiming to compare posterolateral and direct lateral hemiarthroplasty approaches for the treatment of hip fracture.The primary outcome of interest was health-related quality of life at 6 months, measured with the EuroQol 5-Dimensions (EQ-5D-5L) questionnaire.Secondary outcomes of interest included dislocation, fear of falling, activities of daily living, pain, and re-operation.Data from the randomized trial and natural experiment were fused, and pooled effects were reported.The pooled results showed a significantly higher odds of dislocation with the posterolateral approach compared to the direct lateral approach (OR 12.31 [95%CI 2.77, 54.7]).No difference in quality of life scores were observed between the two groups. The rate of... Read More »
Conference Report
2%
Synopsis: 90 acute tibial shaft fractures were included in this randomized trial comparing intramedullary nailing via a suprapatellar approach (n=42) or infrapatellar approach (n=48).The primary outcomes of interest included anterior knee pain on a Visual Analog Scale (VAS) and knee function on the Kujala scale, measured at 6 weeks and 12 months.Secondary outcomes of interest included radiographic alignment, radiation exposure, and non-union.Patients who received suprapatellar intramedullary nailing reported significantly less anterior knee pain and better knee function at both 6 weeks and 12 months (p<0.05 for all). Moreover, significantly less... Read More »
Conference Report
2%
Synopsis: 83 elderly patients with femoral neck fractures were randomized to receive a bipolar hip hemiarthroplasty via a direct anterior approach (DAA; n=40) or an anterolateral approach (ALA; n=43).The outcomes of interest included mobility measured with the Barthel Index, pain on a Visual Analog Scale (VAS), and heterotopic ossification occurrence, all measured up to 1 year post-operation.Pain scores in the first 2 weeks were significantly lower in the DAA group compared to the ALA group.While mobility was significantly better on post-operative day 1 in the DAA group, the ALA group showed superior mobility from week 6 to end of follow-up (1 year post-operation).The rate of heterotopic ossification was also significantly higher in the ALA group in the first 3 months post-operation.The results suggest that DAA may provide superior outcomes in the early post-operative phase, particularly with respect to early mobilization and pain scores. However, mobility may... Read More »
Level 1 RCT
2%
Synopsis: 124 elderly patients (65 completed 5 year follow-up) with displaced proximal humeral fractures were randomized to receive a total shoulder arthroplasty (n=64) or a plate fixation (n=60).The primary outcome of interest was the Constant score.Secondary outcomes of interest included the Oxford Score and radiological outcomes, which were not reported in the conference abstract.Outcomes were assessed at 2 and 5 years post-operation.The results of this study found reverse total shoulder arthroplasty to result in significantly better Constant scores at 5 years post-operation compared to plate fixation.The sub-group analyses found that reverse total shoulder arthroplasty particularly outperformed plate fixation in patients with Type C2 fractures and patients aged 65-74. Read More »
Conference Report
2%
Synopsis: 42 patients with femoral neck fractures were randomized to receive either tranexamic acid (TXA; n=21) or normal saline (n=21).Outcomes of interest included blood loss, drain output within 48 hours, hemoglobin values, and complications at 6 months. TXA significantly reduced... Read More »
Conference Report
2%
Synopsis: 218 patients with open tibia or femur fractures were randomized to receive irrigation using a colloidal silver solution, a bleach solution, or a normal saline solution.The primary outcome of interest was surgical site infection, measured over 1 year follow-up.No significant differences were observed between the three groups, suggesting that bleach solution could be a cost-effective alternative to more conventional irrigation solutions in resource-constrained environments. Time to debridement... Read More »
Conference Report
2%
Synopsis: 40 patients undergoing total knee arthroplasty were randomized to an extended oral tranexamic acid post-operative protocol or a placebo protocol.The outcomes of interest included pain on a Visual Analog Scale (VAS), knee function and health scores (Knee Injury and Osteoarthritis Outcomes Score Joint Replacement [KOOS JR]), knee flexion, terminal knee extension, hemoglobin levels, and adverse events.Follow-up was performed up to 6 weeks post-operation.The extended tranexamic acid group demonstrated lower pain scores at 2 and 6 weeks, improved knee flexion at 6 weeks, and better KOOS JR scores at 2 and 6 weeks compared to the placebo group. No differences in... Read More »
Conference Report
2%
Synopsis: 1022 adult patients undergoing primary total knee arthroplasty (TKA) were randomized to receive either intra-wound vancomycin powder (n=507) or no vancomycin powder (n=515).The primary outcome of interest included the peri-prosthetic joint infection (PJI) rate.The secondary outcomes of interest included surgical site infection (SSI) rates, the incidence of revision for PJI/SSI, and the incidence of wound complications.Intra-wound vancomycin powder showed no differences vs. no vancomycin powder... Read More »
Conference Report
1%
Synopsis: Twenty-seven randomized controlled trials that compared the safety and efficacy of platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC), and hyaluronic acid (HA) were included in this meta-analysis.Outcomes of interest included the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), pain on a Visual Analog Scale (VAS), International Knee Documentation Committee (IKDC), and Lequesne Index Score (LEQ).WOMAC, IKDC, and VAS scores favored PRP against HA.Similarly, in the network meta-analyses comparing BMAC and HA, WOMAC, IKDC, and VAS scores favored BMAC. No differences were... Read More »
Author verified Level 1 Meta Analysis