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14%
Synopsis: Thirty patients with partial-thickness tears of the supraspinatus tendon were randomized to receive a platelet-rich plasma injection (n=15) or corticosteroid injection (n=15).The primary outcome of interest was tear size.The secondary outcome of interest was functional outcomes, measured with the American Shoulder and Elbow Surgeons (ASES) score and the Constant Murley (CM) score.Outcomes were measured at 6 months post-injection.The improvement from baseline in tear size at 6 months in the coronal and sagittal views was significantly greater in the platelet-rich plasma group. Similarly, ASES and... Read More »
Level 1 RCT
8%
Synopsis: 8 randomized controlled trials containing a total of 444 patients with chronic plantar fasciitis were included in this meta-analysis comparing dextrose prolotherapy to other interventions, such as exercise, platelet-rich plasma injection, and extracorporeal shockwave therapy.The pooled outcomes of interest included pain on a Visual Analog Scale (VAS), the Foot Function Index (FFI), the American Orthopaedic Foot and Ankle Society score (AOFAS), and plantar fascia thickness.Dextrose prolotherapy provided a significantly greater reduction in plantar fascia thickness vs.comparators, as well as a greater improvement in foot function in the first 6 months.Whilst overall pooled pain scores were not different between groups, dextrose prolotherapy demonstrated significantly better pooled pain scores vs. nonactive interventions such... Read More »
Level 1 Meta Analysis
5%
Synopsis: Sixty-four patients with de Quervain's tenosynovitis were randomized to receive a local injection of ketorolac (n=31) or triamcinolone acetonide (n=33).Outcomes of interest included pain scores on a Visual Numeric Rating Scale (VNRS), the Disabilities of the Arm, Shoulder and Hand (DASH) score, grip strength and pinch strength, and the need for additional injection, assessed at 6 weeks follow up.The results revealed superior pain scores, DASH scores, and grip strength outcomes in the triamcinolone group vs.the ketorolac group. The need for... Read More »
Level 1 RCT
5%
Synopsis: In this meta-analysis, fifteen randomized controlled trials were included to compare operative (ORIF with locked plates, locked IMN, cemented, uncemented, nonmodular or modular hemiarthroplasty, and reverse shoulder arthroplasty) versus non-operative treatment for proximal humeral fractures.Outcomes of interest were normalized function, pain on the Visual Analog Scale (VAS), and the incidence of reoperation.In the pooled analysis comparing operative treatment with nonoperative treatment, no differences were found between all outcomes. When comparing ORIF... Read More »
Level 1 Meta Analysis
5%
Synopsis: 36 patients with mid-portion Achilles tendinopathy were randomized to receive an endoscopic debridement procedure (n=19) or an endoscopic debridement procedure combined with an intra-operative platelet-rich plasma injection (PRP) (n=17).Outcomes of interest included patient-reported pain, function, and satisfaction (on a Visual Analog Scale), the Victorian Institute of Sports Assessment-Achilles (VISA-A) questionnaire, and radiographic outcomes (tendon thickness and tendinopathic area variation).Outcomes were assessed up to 12 months post-treatment.Additional PRP injection significantly improved patient-reported function and satisfaction in the first 3 months compared to debridement only; function was also significantly better at 12 months in the PRP group. No differences in... Read More »
Level 1 RCT
2%
Synopsis: 54 patients of a broad age range with chronic Achilles tendinopathy were randomized to receive either a platelet-rich plasma injection or saline (placebo).The results of 1 year follow-up indicated that both groups displayed no significant differences in Victorian Institute of Sports Assessment-Achilles scores or ultrasonographic tendon structure. Additionally, majority of... Read More »
Level 1 RCT
2%
Synopsis: 28 inexperienced residents were randomized to prepare for closed reduction and percutaneous pinning of a pediatric supracondylar fracture surgery test, using either a textbook supplemented with an e-Learning module, or with a textbook alone to see whether e-Learning can improve performance and reduce anxiety. In a 60 minute test results and effectiveness survey, residents in E-learning group demonstrated better test scores, more confidence, and comfort with the surgical procedure. Read More »
Conference Report
2%
Synopsis: 13 ACE reports (4 reviews/ meta-analyses, 9 RCTs) were included from the OrthoEvidence database that compared operative versus nonoperative or operative versus operative treatments for displaced midshaft clavicle fractures.The findings of this review demonstrated that surgical procedures led to a lower rate of nonunion and malunion with better functional outcome when compared to nonoperative treatment. Comparisons of operative treatments indicated that an optimal surgical procedure - between plate fixation, nailing, and pin fixation - could not be determined based on union rates or functional outcome. The results of... Read More »
ACE Review
2%
Synopsis: Data from 158 United States randomized controlled trials, investigating 37,625 patients, was analyzed in this systematic review to evaluate the inclusion of, and the reported rates of race and/or ethnicity in orthopaedic evidence.Despite the diverse population in United States, the findings of this analysis demonstrated a deficit in the reporting of data on race or ethnicity by American orthopaedic randomized controlled trials. These findings indicated... Read More »
Author verified Level 1 Meta Analysis
2%
Synopsis: 67 patients with femoroacetabular impingement and complete labral tear scheduled for arthroscopic surgery were randomized to undergo the procedure either with or without an intraarticular injection of platelet-rich-plasma (PRP) at the end of surgery.The purpose of this study was to compare clinical outcomes (modified Harris Hip Score and visual analog scale [VAS] pain) over 24 months postoperatively, and MRI results at 6 months postoperatively.Significant differences were observed in favor of the PRP group in terms of VAS pain 2 days following surgery, and the rate of effusion at the 6 month follow-up. However, no other... Read More »
Author verified Level 2 RCT