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Titrated THC:CBD Improves Pain and Spasticity Compared to Placebo Over 12 Weeks for Resistant MS
Int J Neurosci. 2018 Sep 13:1-10.
Dronabinol effective in reducing neuropathic pain in multiple sclerosis after 48-week treatment
Eur Neurol. 2017;78(5-6):320-329.
Oral THC/CBD spray provides neuropathic pain control in MS patients, with mild/moderate side effects
Clin Ther. 2007 Sep;29(9):2068-79
Oral tetrahydrocannabinol (THC) does not reduce chronic abdominal pain compared to placebo
Clin Gastroenterol Hepatol. 2017 Jul;15(7):1079-1086.e4. doi: 10.1016/j.cgh.2016.09.147
Tetrahydrocannabinol similar in efficacy & safety as placebo in improving spasticity and pain in MS
Clin Ther. 2018 Sep;40(9):1467-1482. doi: 10.1016/j.clinthera.2017.01.016
Dronabinol increases pain threshold compared to placebo for functional chest pain over 4 weeks
Dis Esophagus. 2017 Feb 1;30(2):1-8. doi: 10.1111/dote.12455
Delta 9-THC has better analgesic effect compared to placebo for neuropathic pain over 8 hours
J Pain. 2016 Sep;17(9):982-1000. doi: 10.1016/j.jpain.2016.05.010
The analgesic effect of vaporized cannabis versus placebo on pain
J Pain Res. 2016 Aug 31;9:587-98. doi: 10.2147/JPR.S113138. eCollection 2016
Tetrahydrocannabinol 8mg does not demonstrate better efficacy vs diazepam for chronic pancreatitis
Br J Clin Pharmacol. 2016 Mar;81(3):525-37. doi: 10.1111/bcp.12811
Dronabinol does not cause metabolic disturbances in managing chronic neuropathy pain
Clin Ther. 2015 Oct 1;37(10):2267-74. doi: 10.1016/j.clinthera.2015.07.023
Titrated THC and CBD does not significantly improve spasticity compared to placebo over 4 weeks
J Neurol. 2015 Nov;262(11):2520-7
Inhaled THC demonstrated dose-dependent pain reduction and modest side effect 4 hours post-treatment
J Pain. 2015 Jul;16(7):616-27. doi: 10.1016/j.jpain.2015.03.008
Nabilone safe and effective in pain reduction in combination with gabapentin compared to placebo
Pain Med. 2015 Jan;16(1):149-59. doi: 10.1111/pme.12569
Efficacy of a cannabis-based oromucosal spray in managing peripheral neuropathic pain
Eur J Pain. 2014 Aug;18(7):999-1012. doi: 10.1002/j.1532-2149.2013.00445.x
Oral dronabinol and smoked cannabis have similar psychoactive effects, but peak at different times
Clin J Pain. 2014 Jun;30(6):472-8. doi: 10.1097/AJP.0000000000000022
Cannabis oralmucosal spray does not significantly improve neuropathic pain from multiple sclerosis
J Neurol. 2013 Apr;260(4):984-97. doi: 10.1007/s00415-012-6739-4
Vaporized cannabis improves pain in neuropathic pain disorders
J Pain. 2013 Feb;14(2):136-48. doi: 10.1016/j.jpain.2012.10.009
THC effective for muscle stiffness relief due to MS after 12 weeks of treatment compared to placebo
J Neurol Neurosurg Psychiatry. 2012 Nov;83(11):1125-32. doi: 10.1136/jnnp-2012-302468
Nabilone effective in reducing headache in medication overuse headach patients compared to ibuprofen
J Headache Pain. 2012 Nov;13(8):677-84. doi: 10.1007/s10194-012-0490-1
Nabilone reduces pain and improves sleep and quality of life in diabetic peripheral neuropathic pain
Pain. 2012 Oct;153(10):2073-82. https://dx.doi.org/10.1016/j.pain.2012.06.024