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Significant reduction in 6-year fragility fracture risk with zoledronate vs placebo for osteopenia

N Engl J Med. 2018 Dec 20;379(25):2407-2416. doi: 10.1056/NEJMoa1808082

RCT Metabolic Disorders Elderly Osteopenia Postmenopausal Women Lower Extremity Hip Bone Femur Neck Fracture Novartis Zoledronate Intravenous Infusion Placebo - Hide
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Effects of teriparatide versus risedronate following pertrochanteric fracture fixation

J Bone Joint Surg Am. 2016 Nov 16;98(22):1868-1878

RCT Trauma Osteopenia Osteoporosis Postmenopausal Women Axial Skeleton Spine Spine Lumbar Lower Extremity Hip Bone Femur Fracture Eli Lilly Teriparatide Fixation Oral Risedronate - Hide
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Combination therapy improves site-specific BMD vs. teriparatide & denosumab monotherapies

J Clin Densitom. 2016 Jul-Sep;19(3):346-51

RCT Metabolic Disorders Osteopenia Osteoporosis Postmenopausal Women Fracture Amgen Eli Lilly Denosumab Teriparatide - Hide
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Immediate effects on bone metabolism biomarkers noted with resistance training and walking

BMC Musculoskelet Disord. 2016 Jun 8;17(1):254

RCT Metabolic Disorders Elderly Osteopenia Osteoporosis Women Control Resistance Training Serum Walking - Hide
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Treatment of osteopenia with melatonin effective in increasing BMD in postmenopausal women

J Pineal Res. 2015 Sep;59(2):221-9.

RCT Metabolic Disorders Osteopenia Postmenopausal Women Bone Femur Neck Melatonin Placebo - Hide
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Osteoporosis Choice decision aid improves treatment experience of clinicians and patients

PLoS One. 2015 May 26;10(5):e0128063.

RCT Metabolic Disorders Osteopenia Osteoporosis Women Fracture Decision Aid Usual Care - Hide
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Olive leaf extract improves osteocalcin level & serum lipid profile in osteopenic women

J Nutr Health Aging. 2015;19(1):77-86

RCT General Orthopaedics Osteopenia Postmenopausal Women Axial Skeleton Spine Spine Lumbar BioActor BV Extract Oral Calcium Placebo Serum - Hide
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Evaluating raloxifene in postmenopausal Japanese women with osteoporosis or osteopenia

Clin Interv Aging. 2014 Nov 5;9:1879-1893.

Meta-analysis Metabolic Disorders Osteopenia Osteoporosis Postmenopausal Women Eli Lilly Raloxifene Collagen Observational Prevent - Hide
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Effects of 2.5mg zoledronate are long-lasting and similar to 5mg dose in osteopenic women

J Bone Miner Res. 2014 Jan;29(1):166-72. doi: 10.1002/jbmr.2009.

RCT General Orthopaedics Osteopenia Postmenopausal Women Axial Skeleton Spine Spine Lumbar Lower Extremity Hip Novartis Roche Zoledronate Infusion Placebo - Hide
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Alendronate & zoledronate both reduce hip and vertebral fracture risk compared to placebo

Gynecol Endocrinol. 2013 Dec;29(12):1005-14. doi: 10.3109/09513590.2013.813468. Epub 2013 Sep 25

Meta-analysis Metabolic Disorders Osteopenia Osteoporosis Postmenopausal Women Lower Extremity Hip Joint Vertebral Fracture Alendronate Zoledronate Placebo Zoledronic Acid - Hide
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Bone mass measurements improved with WBV therapy in AIS, osteopenic females

Osteoporos Int. 2013 May;24(5):1623-36. doi: 10.1007/s00198-012-2144-1. Epub 2012 Sep 26

RCT Physical Therapy & Rehab Adolescent Osteopenia Scoliosis Women Observation Vibration WBV - Hide
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Substantial anti-resorptive effects achieved with 1mg and 2.5mg doses of zoledronate

J Clin Endocrinol Metab. 2012 Jan;97(1):286-92. doi: 10.1210/jc.2011-2081. Epub 2011 Nov 9

RCT General Orthopaedics Osteopenia Postmenopausal Women Zoledronate IV Infusion Placebo - Hide
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Positive effect of D-003 on bone mineral density in postmenopausal women

Korean J Intern Med. 2011 Jun;26(2):168-78. doi: 10.3904/kjim.2011.26.2.168. Epub 2011 Jun 1

RCT General Orthopaedics Osteopenia Osteoporosis Postmenopausal Women Axial Skeleton Spine Spine Lumbar Bone Femur Neck Placebo - Hide
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Pulsing electromagnetic field treatment yields no effect on disuse osteopenia (bone loss)

Bioelectromagnetics. 2011 May;32(4):273-82. doi: 10.1002/bem.20632. Epub 2010 Dec 22

RCT General Orthopaedics Osteopenia Upper Extremity Forearm Bone Carpal Radius Fracture Electromagnetic Field PEMF Transducers Sham - Hide
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Alendronate is an effective way of increasing BMD and reducing bone turnover

J Int Med Res. 2011;39(1):302-10

RCT General Orthopaedics Osteopenia Osteoporosis Postmenopausal Women Alendronate Alfacalcidol Control - Hide
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Bone loss at lumbar spine after kidney transplant reduced with IV pamidronate

Osteoporos Int. 2011 Jan;22(1):281-7

RCT Metabolic Disorders Osteopenia Axial Skeleton Spine Spine Lumbar Pamidronate - Hide
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The effect of tai chi on risk factors for falls in postmenopausal women with osteopaenia

Clin Rehabil. 2010 Dec;24(12):1080-90

RCT Physical Therapy & Rehab Falls Osteopenia Postmenopausal Women Axial Skeleton Spine Lower Extremity Hip Control Exercise Factors - Hide
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Antiresorptive effects of single zoledronate dose are sustained for 3 years

J Bone Miner Res. 2010 Oct;25(10):2251-5

RCT Metabolic Disorders Osteopenia Postmenopausal Women Zoledronate Placebo - Hide
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Exercise improves long-term balance and gait in elderly women with osteopenia

Arch Intern Med. 2010 Sep 27;170(17):1548-56. doi: 10.1001/archinternmed.2010.311.

RCT General Orthopaedics Elderly Osteopenia Women Bone Femur Radius Neck Balance Exercise Training - Hide
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Effects of ch-OSA and Ca/Vit D3 administration in osteopenic women

BMC Musculoskelet Disord. 2008 Jun 11;9:85

RCT Metabolic Disorders Osteopenia Women Axial Skeleton Spine Oral Choline-Stabilized Orthosilicic Acid Placebo Vit D3 - Hide
Showing 1 - 20 of 20