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Intra-articular mesenchymal stem cells possibly beneficial for meniscus regeneration
April 2014
Intra-articular mesenchymal stem cells possibly beneficial for meniscus regeneration
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:1
Adult human mesenchymal stem cells delivered via intra-articular injection to the knee following partial medial meniscectomy: a randomized, double-blind, controlled study
J Bone Joint Surg Am. 2014 Jan 15;96(2):90-8. doi: 10.2106/JBJS.M.00058Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
60 patients undergoing a partial meniscectomy were randomized to receive a single postoperative injection of allogeneic human mesenchymal stem cells (50x10^6 or 150x10^6 cell count) or a control vehicle injection of sodium hyaluronate, 7-10 days after surgery. The purpose of this study was to determine if a single intra-articular injection of mesenchymal stem cells caused meniscal regeneration ove...
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