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ACE Report #9605
Ace Report Cover Osteoarthritis

Leukocyte-poor platelet-rich plasma vs hyaluronic acid in treatment of symptomatic knee OA


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Hyaluronic Acid Versus Platelet-Rich Plasma: A Prospective, Double-Blind Randomized Controlled Trial Comparing Clinical Outcomes and Effects on Intra-articular Biology for the Treatment of Knee Osteoarthritis

Am J Sports Med. 2017 Feb;45(2):339-346

Contributing Authors: BJ Cole V Karas K Hussey LA Fortier K Pilz

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Synopsis

111 patients with Kellgren-Lawrence grade I-IV symptomatic knee osteoarthritis were randomized to three weekly intraarticular injections of either leukocyte-poor platelet-rich plasma (LP-PRP) or hyaluronic acid. Patients were assessed for pain and function over a 52-week follow-up. The primary outcome measure, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score, d...

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