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Pediatric cerebral palsy: AbobotulinumtoxinA safe + efficacious in equinus foot deformity

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Ace Report Cover
July 2016

Pediatric cerebral palsy: AbobotulinumtoxinA safe + efficacious in equinus foot deformity

Vol: 5| Issue: 7| Number:65| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

AbobotulinumtoxinA for Equinus Foot Deformity in Cerebral Palsy: A Randomized Controlled Trial

Pediatrics. 2016 Feb;137(2):1-9

Contributing Authors:
MR Delgado A Tilton B Russman O Benavides M Bonikowski J Carranza E Dabrowski N Dursun M Gormley M Jozwiak D Matthews I Maciag-Tymecka E Unlu E Pham A Tse P Picaut

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Synopsis

241 pediatric patients (aged 2-17 years), with spasticity associated with cerebral palsy and dynamic equinus foot deformity, were randomized into three groups receiving either placebo treatment, 10 or 15U/kg/leg doses of botulinum neurotoxin type-A (BoNT-A) formulation (abobotulinumtoxinA). The purpose of this study was to assess the safety and efficacy of BoNT-A injections, in the gastrocnemius a...

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