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RCT
ACE Report #8434
Ace Report Cover Osteoarthritis

The addition of Hylan G-F 20 injections to standard care beneficial for knee OA


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

A prospective, randomized, pragmatic, health outcomes trial evaluating the incorporation of hylan G-F 20 into the treatment paradigm for patients with knee osteoarthritis (Part 1 of 2): clinical results

Osteoarthritis Cartilage. 2002 Jul;10(7):506-17

Contributing Authors: JP Raynauld GW Torrance PA Band CH Goldsmith P Tugwell V Walker M Schultz N Bellamy Canadian Knee OA Study Group

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Synopsis

255 patients, over the age of 40, with a diagnosis of knee osteoarthritis were randomized to receive either appropriate care alone or 3 intra-articular injections of hylan G-F 20 at 1-week intervals in addition to appropriate care. The purpose of this randomized controlled trial was to determine the clinical effectiveness of hylan G-F 20 injections in terms of disease-specific outcomes and health-...

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