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Meta-analysis
ACE Report #8391
Ace Report Cover Osteoarthritis

Network meta-analysis of glucosamine and/or chondroitin, celecoxib, and placebo in knee OA


Study Type:Meta analysis
OE Level Evidence:2
Journal Level of Evidence:N/A

Effectiveness and safety of Glucosamine, chondroitin, the two in combination, or celecoxib in the treatment of osteoarthritis of the knee

Sci Rep. 2015 Nov 18;5:16827

Contributing Authors: C Zeng J Wei H Li YL Wang DX Xie T Yang SG Gao YS Li W Luo GH Lei

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Synopsis

A total of 54 studies were selected for inclusion in a network meta-analysis comparing the effects of celecoxib, glucosamine, chondroitin, glucosamine + chondroitin, and placebo on pain and functional outcome in patients with knee osteoarthritis. Regarding pain, all four treatment groups (celecoxib, glucosamine, chondroitin, glucosamine + chondroitin) demonstrated a significant positive effect on ...

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