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Meta-analysis
ACE Report #7832
Ace Report Cover Osteoarthritis

IA injection of US-approved viscosupplements safe and effective at 26 weeks in knee OA


Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Safety and efficacy of US-approved viscosupplements for knee osteoarthritis: a systematic review and meta-analysis of randomized, saline-controlled trials

J Pain Res. 2015 May 7;8:217-28

Contributing Authors: V Strand LF McIntyre WR Beach LE Miller JE Block

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Synopsis

29 randomized controlled trials, with a total of 4,886 patients were included in this meta-analysis to analyze the safety and efficacy of US-approved viscosupplements in symptomatic knee osteoarthritis (OA) treatment. Results indicated that intra-articular injection of viscosupplements may be safe and effective through 26 weeks, as they resulted in large treatment effects for knee pain and functio...

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