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The effect of alendronate post-TKA on bone mineral density and clinical outcome
December 2015
The effect of alendronate post-TKA on bone mineral density and clinical outcome
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Effect of one-year post-operative alendronate treatment on periprosthetic bone after total knee arthroplasty: a seven-year randomised controlled trial of 26 patients
Bone Joint J. 2015 Mar;97-B(3):337-45Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
26 patients who underwent total knee arthroplasty (TKA) were randomized to one of two groups: alendronate and calcium supplementation for 1 year postoperatively, or calcium alone for 1 year postoperatively. The purpose of this study was to examine the effect of alendronate on periprosthetic bone mineral density (BMD) postoperatively. Follow-up was performed for 7 years. The alendronate group demon...
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