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Volume:1 Issue:8 Number:167 ISSN#:2563-5476
RCT
ACE Report #754
Ace Report Cover Metabolic Disorders

Teriparatide increases BMD in patients with glucocorticoid-Induced osteoporosis


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Teriparatide or Alendronate in Glucocorticoid-Induced Osteoporosis

N Engl J Med. 2007 Nov 15;357(20):2028-39

Contributing Authors: KG Saag E Shane S Boonen F Marín DW Donley KA Taylor GP Dalsky R Marcus

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Synopsis

428 patients with glucocorticoid-induced osteoporosis were randomised to receive one of two treatments. The first group received a treatment of 20 μg teriparatide daily while the second group received a 10 mg alendronate treatment. The primary outcome was change in bone mineral density at the lumbar spine from baseline to the 18-month follow-up. Results indicated that bone mineral density increas...

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