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Manipulation from 1-7 days after CCH injection is feasible for Dupuytren contractures

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Ace Report Cover
December 2014

Manipulation from 1-7 days after CCH injection is feasible for Dupuytren contractures

Vol: 3| Issue: 12| Number:7| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:1

Prospective Randomized Controlled Trial Comparing 1- Versus 7-Day Manipulation Following Collagenase Injection for Dupuytren Contracture

J Hand Surg Am. 2014 Oct;39(10):1933-1941.e1. doi: 10.1016/j.jhsa.2014.07.010. Epub 2014 Sep 4.

Contributing Authors:
DT Mickelson SS Noland AJ Watt KM Kollitz NB Vedder JI Huang

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Synopsis

43 patients (46 digits) with Dupuytren contracture were randomly allocated to undergo manipulation at 1 or 7 days after collagenase Clostridium histolyticum (CCH) injection, with the purpose of comparing the efficacy and side effects of postponing manipulation. At 30 days follow-up, the efficacy of CCH was preserved in the 7-day manipulation group, suggesting manipulation can be scheduled at the c...

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