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Volume:3 Issue:8 Number:52 ISSN#:2563-5476
ACE Report #6650
Ace Report Cover Osteoarthritis

Efficacy of polynucleotide solution vs hyaluronic acid for knee osteoarthritis

How to Cite

OrthoEvidence. Efficacy of polynucleotide solution vs hyaluronic acid for knee osteoarthritis. ACE Report. 2014;3(8):52. Available from: https://myorthoevidene.com/AceReport/Report/6650

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

A randomized double-blind clinical trial on the treatment of knee osteoarthritis: the efficacy of polynucleotides compared to standard hyaluronian viscosupplementation

Knee. 2014 Jun;21(3):661-8

Contributing Authors: LS Giarratana BM Marelli C Crapanzano SE De Martinis L Gala M Ferraro N Marelli W Albisetti

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72 patients with knee osteoarthritis were randomized to intra-articular injections of either Condrotide or hyaluronic acid. Condrotide is a gel containing a solution of polynucleotides. The purpose of this study was to compare the efficacy of Condrotide to that of hyaluronic acid (HA), a standard injection therapy for knee osteoarthritis. Assessment of the KOOS and pain was performed at baseline, ...

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