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Volume:2 Issue:2 Number:41 ISSN#:2563-5476
RCT
ACE Report #5805
Ace Report Cover Arthroplasty

Topical tranexamic acid reduces blood loss and transfusion rate following THA


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Topical (Intra-Articular) Tranexamic Acid Reduces Blood Loss and Transfusion Rates Following Total Hip Replacement: A Randomized Controlled Trial (TRANX-H)

J Bone Joint Surg Am. 2013 Nov 6;95(21):1969-74

Contributing Authors: S Alshryda J Mason P Sarda A Nargol N Cooke H Ahmad S Tang R Logishetty M Vaghela L McPartlin AP Hungin

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Synopsis

One hundred and sixty-one patients scheduled to receive unilateral primary total hip replacement were randomly assigned into 1 of 2 groups, a tranexamic group or a placebo, to test the effect of topical application of tranexamic acid has on blood loss and transfusion in patients undergoing total hip arthroplasty. The results of the study indicated that topical administration of tranexamic acid was...

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