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ACE Report #4686
Ace Report Cover Hand & Wrist

Single intra-articular injection of hylarunon not effective for treatment of first MTPJ OA


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Effectiveness of intra-articular hyaluronan (Synvisc, hylan G-F 20) for the treatment of first metatarsophalangeal joint osteoarthritis: a randomised placebo-controlled trial

Ann Rheum Dis. 2011 Oct;70(10):1838-41. doi: 10.1136/ard.2011.153049. Epub 2011 Jul 25

Contributing Authors: SE Munteanu GV Zammit HB Menz KB Landorf CJ Handley A Elzarka J Deluca

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Synopsis

151 patients with osteoarthritis (OA) of the first metatarsophalangeal joint (MTPJ) were randomized to determine the efficacy of intra-articularly injected hyaluronan for symptomatic treatment of this condition. Patients received a single injection of either Hylan G-F 20 or saline placebo, and were followed for 6 months following the injection. The results indicated that there were no differences ...

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