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Perioperative administration of cyclooxygenase-2 inhibitors reduces pain in TKA patients
April 2013
Perioperative administration of cyclooxygenase-2 inhibitors reduces pain in TKA patients
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A
Perioperative administration of selective cyclooxygenase-2 inhibitors for postoperative pain management in patients after total knee arthroplasty
J Arthroplasty. 2013 Feb;28(2):207-213.e2. doi: 10.1016/j.arth.2012.04.008. Epub 2012 Jun 7Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
8 studies (571 patients) were analyzed to evaluate the postoperative effects of selective cyclooxygenase-2 (COX-2) inhibitors when administered to patients during TKA. Results indicated that COX-2 inhibitors administered during TKA resulted in reduced postoperative pain, opioid consumption, and incidence of complications. Blood loss during the first 24 hours following surgery did not differ betwee...
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