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Canakinumab effective in treating systemic juvenile idiopathic arthritis
May 2013
Canakinumab effective in treating systemic juvenile idiopathic arthritis
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
N Engl J Med. 2012 Dec 20;367(25):2396-406. doi: 10.1056/NEJMoa1205099Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
177 patients, suffering from systemic juvenile idiopathic arthritis (JIA) with active systemic features, who had been chosen to participate in two trials between July 2009 and December 2010, were randomised into two groups to either receive canakinumab or a placebo. Patients in Trial 1 received either canakinumab or the placebo for 29 days. Trial 2 incorporated a two-part withdrawal design, which ...
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