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The OPAL Trial: Opioid Analgesia For Acute Low Back & Neck Pain
January 2024
The OPAL Trial: Opioid Analgesia For Acute Low Back & Neck Pain
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial.
Lancet . 2023 Jul 22;402(10398):304-312.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
347 patients with acute non-specific low back and neck pain were randomized to receive guideline-recommended care with either a judicious short-course opioid analgesic regimen (n=174) or a placebo (n=173). The primary outcome of interest was pain intensity at 6 weeks measured using the Brief Pain Inventory (BPI) Pain Severity subscale. Secondary outcomes included BPI-pain severity at 2, 4, 12, 26...
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