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Nefopam Versus Placebo for Postoperative Pain Management Following Spinal Fusion Surgery
February 2024
Nefopam Versus Placebo for Postoperative Pain Management Following Spinal Fusion Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Perioperative Intravenous Nefopam on Pain Management and Ambulation after Open Spine Surgery: A Randomized Double-Blind Controlled Study.
Asian Spine J . 2023 Aug;17(4):632-638.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
100 patients undergoing lumbar decompression and fusion were randomized to receive either nefopam (n=50) or a saline placebo (n=50). The primary outcome of interest is morphine consumption after 24 hours. Secondary outcomes of interest included total morphine equivalents consumption, PainDetect-Questionnaire (PDQ), length of stay, time to PACU discharge, upright position, ambulation, first urine c...
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