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Celecoxib + Pregabalin for Managing Postoperative Analgesia in Patients Undergoing TKA
December 2023
Celecoxib + Pregabalin for Managing Postoperative Analgesia in Patients Undergoing TKA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Positive Preemptive Analgesia Effectiveness of Pregabalin Combined with Celecoxib in Total Knee Arthroplasty: A Prospective Controlled Randomized Study.
Pain Res Manag . 2023 Jan 12:2023:7088004.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
160 patients with knee osteoarthritis, undergoing total knee arthroplasty were randomized to receive either pregabalin + celecoxib (n=40), celecoxib alone (n=40), pregabalin alone (n=40), or placebo (n=40). Outcomes of interest included pain at rest and with movement on a Visual Analog Scale (VAS), sufentanil cumulative dose, high-sensitivity C-reactive protein (hs-CRP), range of motion (ROM), and...
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