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No significant effect of topical FS or TXA on blood loss in cases of sub-capital femoral fracture

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Ace Report Cover
June 2019

No significant effect of topical FS or TXA on blood loss in cases of sub-capital femoral fracture

Vol: 8| Issue: 6| Number:11| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Prevention of postoperative bleeding in hip fractures treated with prosthetic replacement: efficacy and safety of fibrin sealant and tranexamic acid. A randomised controlled clinical trial (TRANEXFER study)

Arch Orthop Trauma Surg. 2019 May;139(5):597-604. doi: 10.1007/s00402-018-3089-4

Contributing Authors:
MJ Martinez-Zapata X Aguilera A Bosch M Jordan JC Gonzalez P Castillon M Salomo JA Hernandez L Ruiz JM Mora P Camacho-Carrasco S Prat-Fabregat A Rodriguez-Arias

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Synopsis

161 patients with a sub-capital femoral fracture and undergoing arthroplasty were randomized to one of three groups: topical fibrin sealant application, topical tranexamic acid applications, or standard haemostasis through electrocoagulation alone. The primary outcome of this study was volume of blood loss to postoperative drainage. Results demonstrated no significant differences between the three...

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