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Hylan injection no different than placebo injection for pain improvement in hip osteoarthritis
July 2020
Hylan injection no different than placebo injection for pain improvement in hip osteoarthritis
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Evaluating the use of intra-articular injections as a treatment for painful hip osteoarthritis: a randomized, double-blind, multicenter, parallel-group study comparing a single 6-mL injection of hylan G-F 20 with saline
Osteoarthritis Cartilage. 2019 Jan;27(1):59-70. doi: 10.1016/j.joca.2018.08.018.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
357 patients with hip osteoarthritis were randomized to a single intraarticular injection of either hylan G-F 20 or placebo saline. Patients were assessed over 26-week follow-up for outcome on improvement in the first question of the WOMAC Pain subscale (WOMAC A1), response rate on the WOMAC A1 (minimum 2-pt improvement), the WOMAC Pain subscale overall, the WOMAC Function subscale, and the incide...
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