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RCT
ACE Report #10795
Ace Report Cover Osteoarthritis

IA versus oral hyaluronic acid in the treatment of patients with KL grade I-II knee osteoarthritis


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Clinical comparison of oral administration and viscosupplementation of hyaluronic acid (HA) in early knee osteoarthritis

Musculoskelet Surg. 2017 Apr;101(1):45-49. doi: 10.1007/s12306-016-0428-x

Contributing Authors: M Ricci GM Micheloni M Berti F Perusi E Sambugaro E Vecchini B Magnan

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Synopsis

60 patients with Kellgren-Lawrence grade I-II knee osteoarthritis were randomized to treatment with either intraarticular hyaluronic acid or oral hyaluronic acid. Patients allocated to IAHA were administered three weekly injection, and patients allocated to oral HA were given daily tablets to take for 40 days. Outcome measures included pain on a visual analog scale and the American Knee Society Sc...

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