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High-dose vitD has no significant effect, positive or negative, compared to low-dose after TKA

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Ace Report Cover
August 2018

High-dose vitD has no significant effect, positive or negative, compared to low-dose after TKA

Vol: 7| Issue: 8| Number:14| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:1
Journal Level of Evidence:N/A

Recovery after unilateral knee replacement due to severe osteoarthritis and progression in the contralateral knee: a randomised clinical trial comparing daily 2000 IU versus 800 IU vitamin D

RMD Open. 2018 Jul 9;4(2):e000678. doi: 10.1136/rmdopen-2018-000678

Contributing Authors:
R Rizzoli D Felson B Dawson-Hughes HA Bischoff-Ferrari WC Willett HB Staehelin EJ Orav A Egli K Fischer J Hodler A von Eckardstein G Freystaetter U Meyer T Guggi P Burckhardt S Schietzel P Chocano-Bedoya R Theiler

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Synopsis

273 patients age 60 or older who had undergone unilateral total knee replacement were included in this study to determine if differing doses fo vitamin D had an effect on falls, functional outcome, and radiographic progression of osteoarthritis in the contralateral knee. Patients were randomized to receive 800IU vitamin D per day or 2000IU vitamin D per day. Outcomes of interest included falls, fu...

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