Forty-three patients with advanced degenerative osteoarthritis (OA) knee were randomized to receive isokinetic training (n=14), isotonic training (n=15), or home isometric exercise (n=14). The primary outcome of interest was the time to complete the Timed Up and Go (TUG) test. Secondary outcomes included peak torque of knee flexion and extension at 60 and 120 degrees per second, the Short-Form 36 Health Survey (SF-36), and the Western Ontario and McMaster Universities Arthritis Index (WOMAC). Outcomes were assessed before and after a four-week training period. Overall, the results of the study revealed that isokinetic training significantly improved TUG performance and strength gains, while isotonic training achieved better strength gains but not functional performance. The findings suggest that both isokinetic and isotonic exercises are beneficial for patients post-TKR, with isokinetic training being particularly effective for functional recovery.