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Extended thromboprophylaxis beneficial after total knee arthroplasty

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Ace Report Cover
November 2014

Extended thromboprophylaxis beneficial after total knee arthroplasty

Vol: 3| Issue: 11| Number:31| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Short versus extended thromboprophylaxis after total knee arthroplasty: a randomized comparison

Thromb Res. 2010 Oct;126(4):e298-304

Contributing Authors:
MT Barrellier B Lebel JJ Parienti P Mismetti JJ Dutheil C Vielpeau PROTHEGE study group GETHCAM study group

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Synopsis

857 patients having undergone total knee arthroplasty (TKA) were randomized to receive either short term thromboprophylaxis, where therapy would stop at day 10 +/- 2, or extended thromboprophylaxis, where therapy would stop at day 35 +/- 5. Patients were assessed for proximal or symptomatic deep vein thrombosis (DVT), pulmonary embolism (PE), major bleeding, thrombocytopenia, and mortality up to d...

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