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Safety & Efficacy of Imrecoxib Vs Celecoxib In Total Hip Arthroplasty: A Non-Inferiority Study

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Ace Report Cover
December 2023

Safety & Efficacy of Imrecoxib Vs Celecoxib In Total Hip Arthroplasty: A Non-Inferiority Study

Vol: 305| Issue: 3| Number:6| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Postoperative analgesic efficacy and safety of imrecoxib versus celecoxib in hip osteoarthritis patients undergoing total hip arthroplasty: a multi-center, randomized, controlled, non-inferiority study.

Inflammopharmacology . 2023 Aug;31(4):1813-1822.

Contributing Authors:
K Zhang X Miao L Jiang S Cui Z Liu Z Wang

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Synopsis

156 patients undergoing total hip arthroplasty (THA) for hip osteoarthritis were randomized to receive either celecoxib (n=78) or imrecoxib (n=78). Outcomes of interest included pain at rest and with movement on a Visual Analog Scale (VAS), opioid consumption, Harris Hip Scores (HHS), quality of life on the EuroQol 5 Dimensions (EQ-5D) questionnaire, and the incidence of adverse events, all measur...

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