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Oral acetaminophen demonstrates similar analgesic efficacy to IV acetaminophen in TKA and THA
May 2018
Oral acetaminophen demonstrates similar analgesic efficacy to IV acetaminophen in TKA and THA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Randomized trial of oral versus intravenous acetaminophen for postoperative pain control
Am J Health Syst Pharm. 2018 Mar 15;75(6):367-375Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
515 patients scheduled for total knee or hip arthroplasty were randomized to either oral acetaminophen or intravenous acetaminophen as part of their postoperative analgesia regimen. The primary outcome was opioid use over the first 24 hours after surgery. The main secondary outcome was pain score on a numeric rating scale after 4 and 24 hours. Results demonstrated no significant differences betwee...
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