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You are viewing the most viewed ACE Reports by Orthopaedic Surgeons over the last 30 days in all specialties.

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Synopsis: The present study is a meta-analysis evaluating the efficacy of autologous whole blood (AWB) therapy versus corticosteroid injections in the treatment of epicondylopathy and plantar fasciopathy (PF).The primary outcome was pain relief at 2-6, 8-13, and 24-26 weeks.The authors included a total of 9 RCTs, and found statistically significant results in favour of corticosteroids at 2-6 weeks for patients with plantar fasciopathy, and in favour of AWB as early as 8 weeks up to 24 weeks for individuals with epicondylopathy. Read More »
Author verified Level 1 Meta Analysis
5%
Synopsis: 22 randomized controlled trials were included in this network meta-analysis, that included over 10 injectable treatments, to evaluate comparative efficacy for the management of plantar faciopathy.The primary outcome of this study was pain relief.At 0-2 month follow-up, micronized dehydrated human amniotic/chorionic membrane was the most likely treatment to be effective for pain relief.At 2-6 months, botulinum toxin A was the treatment most likely to be effective for pain relief, while a treatment most likely to be effective beyond 12 months could not be identified from the limited amount of evidence available at this time point.The lack of trials available was a limiting factor of this network meta-analysis, exemplified by the lack of studies reporting data on micronized dehydrated human amniotic/chorionic membrane beyond 2 months. Further trials are... Read More »
Level 1 Meta Analysis
5%
Synopsis: Seven randomized controlled trials were included in this systematic review and meta-analysis to compare functional outcome measures between patient-specific instrumentation and conventional instrumentation in total knee arthroplasty.Pooled outcomes included the Knee Society Knee Score, Knee Society Functional Score, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, the Knee Injury and Osteoarthritis Outcome Score (KOOS), and visual analog scale (VAS) scores. Results demonstrated no... Read More »
Level 2 Meta Analysis
3%
Synopsis: 77 patients with symptomatic, Kellgren-Lawrence grade II-IV knee osteoarthritis were randomized to intraarticular hyaluronic acid (IAHA) injections with or without an additional, single periarticular lidocaine-corticosteroid injection (PALCI) at the beginning of treatment.The purpose of this study was to determine if the addition of PALCI to IAHA had a significant effect on pain after 1, 3, 6, 12, 26 and 52 weeks.Visual analog pain scores demonstrated significantly lower pain scores in the IAHA+PALCI group compared to the IAHA group at 1 and 3 weeks, while no significant differences between groups at 6, 12, 26 or 52 weeks. A significant within-group... Read More »
Level 2 RCT
2%
Synopsis: 553 leisure-time runners were randomized to three groups that differed only in the heel-to-toe drop (10mm, 6mm, or 0mm) of their running shoes.The investigators measured the risk of injury over 6 months. Overall, there were... Read More »
Author verified Level 1 RCT
1%
Synopsis: 50 patients scheduled for posterior pedicle screw fixation of a thoracolumbar fracture were randomized to surgical wound injection of methylene blue or saline.The purpose of this study was to compare postoperative pain and disability between groups at 48 hours postoperatively and at 2- and 6-month follow-up. Results demonstrated significantly... Read More »
Level 2 RCT
1%
Synopsis: 84 Kenyan patients with an open tibial fracture were randomized to a 24-hour prophylactic antibiotic administration protocol or a 5-day prophylactic antibiotic administration protocol.The purpose of this study was to compare the infection rate after 14 days between these two prophylactic antibiotic administration protocols. Results demonstrated no... Read More »
Author verified Level 2 RCT
1%
Synopsis: 190 patients undergoing partial meniscectomy during which chondral lesions were identified were randomized to either debridement or no debridement of the chondral lesions.Patients were followed up for 12 months postoperatively for clinical scores related to pain, function, and quality of life. At 12 months,... Read More »
RCT
1%
Synopsis: 150 women with osteoporosis or osteopenia were randomized to one of three groups; one group underwent a single session of resistance exercises, one group underwent a single session of simply walking, and one group was a control with no intervention.The purpose of this study was to examine and compare pre- and post-intervention serum levels of bone-specific alkaline phosphatase (BALP), C-terminal cross-linked telopeptide of type I collagen (CTX) and sclerostin between groups.No group demonstrated a significant change in BALP levels. CTX levels were... Read More »
Level 2 RCT
1%
Synopsis: 474 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were included in a 3-year, double-blind, RCT to evaluate the effect of vitamin D supplementation on the rate of radiographic disease progression.Compared to a placebo group, patients treated with vitamin D supplementation did not demonstrate a slower rate of joint space narrowing (JSN) on radiographs over the 3-year follow-up.There were also no significant differences between groups in pain, stiffness, or function. Read More »
Level 2 RCT