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100%
5%
Synopsis: 348 patients with femoroacetabular impingement syndrome were randomized to either arthroscopic intervention or a personal hip therapy programme.Patients were assessed after 6 and 12 months (primary endpoint) using the International Hip Outcome Tool (iHOT-33; primary outcome), the EQ-5D-5L and VAS, and the SF-12 measures, and were monitored for any adverse events. A cost-utility analysis was performed using quality-adjusted life-years generated from results on the EQ-5D-5L.Results demonstrated significantly greater iHOT-33 scores at 12 months in the arthroscopy group compared to the personalized hip therapy group, and the difference exceeded the minimum clinically important difference (MCID) threshold.Secondary outcome measures did not significantly differ between groups. The cost-effectiveness of... Read More »
Level 2 RCT
3%
Synopsis: 126 patients scheduled for arthroscopic rotator cuff repair were randomized to one of four shoulder skin preparation methods: a solution or 1% chlorhexidine gluconate and 70% isopropyl alcohol with or without an antibacterial adhesive drape, or a solution of povidone-iodine with or without an antibacterial adhesive drape.The purpose of this study was to determine if skin preparation with chlorhexidine plus a drape demonstrated a significantly lower rate of Propionibacterium acnes (P.acnes) suture colonization compared to the other three groups.Compared to the povidone-iodine without drape group, the chlorhexidine plus drape group demonstrated a significantly lower incidence of positive culture identification. Statistical comparisons to... Read More »
Author verified Level 2 RCT
2%
Synopsis: 97 patients with an acute syndesmotic injury were randomized to surgical stabilization with either a suture button device or a syndesmotic screw.Patients were followed-up for results on function, pain, and radiological outcome over a 2-year follow-up.Results demonstrated that the suture button device was significantly favoured over a syndesmotic screw for functional outcome from 6 months to 2 years, for dynamic pain scores from 1 year to 2 years, and the rate of malreduction (ie. loss of reduction... Read More »
Author verified Level 2 RCT
1%
Synopsis: Three randomized controlled trials were included in this meta-analysis comparing pain and functional improvement between operative and nonoperative treatment for full-thickness rotator cuff tears.Follow-up was 12 months in each study. Results demonstrated that... Read More »
Author verified Level 1 Meta Analysis
1%
Synopsis: A total of 8 randomized controlled trials were included for data on efficacy, and 9 randomized controlled trials were included for data on harms, in this meta-analysis which investigated the effects of vitamin D and/or calcium supplementation in community-dwelling adults over the age of 50 years.Overall, quantitative and qualitative assessment of fractures rates from efficacy studies demonstrated no significant differences between vitamin D alone, calcium alone, and vitamin D plus calcium compared to placebo. In the harms... Read More »
Author verified Level 1 Meta Analysis
1%
Synopsis: 1583 patients with symptomatic knee osteoarthritis were randomized to either glucosamine monotherapy, chondroitin monotherapy, combined glucosamine and chondroitin therapy, celecoxib 200mg daily, or placebo.Patients were assessed over 24 weeks of treatment.In the primary analysis, only the celecoxib group demonstrated a significantly higher rate of patients attaining the primary efficacy endpoint - a reduction of WOMAC pain by a minimum of 20% relative to baseline - compared to placebo. However, when only... Read More »
RCT
1%
Synopsis: 60 patients scheduled for total knee arthroplasty were randomized to either uncemented fixation with hydroxyapatite-coated components, or to cement fixation.Patients were assessed for component migration via maximum total point motion using radiostereometric analysis.Results demonstrated significantly greater total MTPM after 5 years in the uncemented group compared to the cemented group, but no significant difference between groups in the change in MTPM from 1 year 5 years. Therefore, the results... Read More »
Level 2 RCT
1%
Synopsis: Five randomized controlled trials were included in this meta-analysis comparing the rates of venous thromboembolism and clinically-relevant venous thromboembolism after operative management of fractures in the tibia and distally between chemoprophylaxis groups and control groups. While a significant reduction in the incidence of venous thromboembolism overall was observed with chemoprophylaxis, no significant difference between groups was observed in the incidence of clinically-important venous thromboembolism. Read More »
Conference Report
1%
Synopsis: Five randomized controlled trials and one prospective cohort study were analyzed with a total of 679 patients and 739 knees in this level II meta-analysis comparing topical and intravenous administration of tranexamic acid for patients undergoing total knee arthroplasty.The purpose of this analysis was to investigate whether there was a difference in efficacy between the two modes of administration.No significant differences were found between topical and intravenous administration regarding amount of blood lost postoperatively, number of transfusions required for each patient, and the rate of thromboembolic complications. The results indicated... Read More »
Author verified Level 2 Meta Analysis
1%
Synopsis: 136 patients scheduled for total knee arthroplasty were randomized to an ultracongruent tibial insert or a posterior-stabilized total knee implant.Patients were assessed over a 1-year follow-up.Groups did not demonstrate any significant differences in knee range of motion or function on the UCLA activity score at 1 year. Oxford Knee Scores... Read More »
Level 2 RCT