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Intra-articular methadone is ineffective in reducing pain after ACL reconstruction
August 2013
Intra-articular methadone is ineffective in reducing pain after ACL reconstruction
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
The Effect of Intra-Articular Methadone on Postoperative Pain Following Anterior Cruciate Ligament Reconstruction
J Bone Joint Surg Am. 2005 Jan;87(1):140-4Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
65 patients who were undergoing primary anterior cruciate ligament (ACL) reconstruction were randomized to receive 9.5 mL of bupivacaine with 0.5 mL of 5 mg of methadone, 5 mg of morphine, or 0.5 mL saline solution. Over 7 days, there was no difference between the methadone group and the control group in pain scores or in the amount of inpatient and outpatient supplemental analgesia required. Howe...
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