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Effect of Bamlanivimab (LY-CoV555) Antibody Treatment on Viral Load & Clinical Outcomes for COVID-19

N Engl J Med. 2020 Oct 28;():. 10.1056/NEJMoa2029849

RCT General Orthopaedics Infection Eli Lilly Placebo Protein Bamlanivimab (LY-CoV555) - Hide

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No Clinical Benefit of LY-CoV555 Antibodies Plus Remdesivir in Hospitalized COVID-19 Patients

N Engl J Med. 2021 11-Mar;():. 10.1056/NEJMoa2033130

RCT General Orthopaedics Placebo Humanized monoclonal antibody COVID-19 SARS-CoV-2 Monoclonal Antibody - Hide

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Juvenile RA: Fewer disease flares with Adalimumab (TNF Antibody)

N Engl J Med. 2008 Aug 21;359(8):810-20

RCT Pediatric Orthopaedics Arthritis Abbott Methotrexate Adalimumab Placebo - Hide

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Tocilizumab treatment in systemic juvenile idiopathic arthritis

N Engl J Med. 2012 Dec 20;367(25):2385-95. doi: 10.1056/NEJMoa1112802

RCT Pediatric Orthopaedics Children Arthritis Inflammation Hoffmann-La Roche Roche Ether Placebo Receptor Antibody Tocilizumab - Hide

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Tanezumab effectively and safely reduces OA hip pain and improves physical function

Arthritis Rheum. 2013 Jul;65(7):1795-803. doi: 10.1002/art.37950

RCT Osteoarthritis Nerve Lower Extremity Hip Arthritis Pain Pfizer Placebo Tanezumab - Hide

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Lower incidence of vertebral fracture with romosozumab vs placebo for osteoporosis

N Engl J Med. 2016 Oct 20;375(16):1532-1543

RCT Metabolic Disorders Osteoporosis Postmenopausal Women Lower Extremity Hip Bone Femur Joint Vertebral Neck Fracture Amgen UCB Pharma Denosumab Placebo Romosozumab Subcutaneous Injection - Hide

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Support for physical distancing, face masks, and eye protection to prevent transmission of COVID-19

. 2020 June 1;():. https://doi.org/10.1016/S0140-6736(20)31142-9

Meta-analysis General Orthopaedics Infection Control Prevention Program Physical distancing Physical distancing Facemask Facemask Eye protection Eye protection - Hide

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Salmon calcitonin appears ineffective in the management of knee OA treatment in 2 RCTs

Osteoarthritis Cartilage. 2015 Apr;23(4):532-43.

RCT Osteoarthritis Lower Extremity Knee Arthritis Oral Salmon Calcitonin - Hide

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Diclofenac, ibuprofen, and celecoxib improve function and pain in knee OA patients

Osteoarthritis Cartilage. 2013 Sep;21(9):1400-8

RCT Osteoarthritis Lower Extremity Knee Arthritis Inflammation Pain Ibuprofen Celecoxib Diclofenac Nonsteroidal TKA - Hide

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Romosozumab versus placebo, alendronate, and teriparatide for postmenopausal osteoporosis

Climacteric. 2018 Apr;21(2):189-195

Meta-analysis Metabolic Disorders Osteoporosis Postmenopausal Women Alendronate Teriparatide Placebo Romosozumab - Hide

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Canakinumab effective in treating systemic juvenile idiopathic arthritis

N Engl J Med. 2012 Dec 20;367(25):2396-406. doi: 10.1056/NEJMoa1205099

RCT Pediatric Orthopaedics Arthritis Novartis Glucocorticoid Canakinumab Placebo - Hide

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Efficacy of tanezumab vs. placebo on pain, function, safety for patients with knee OA

PLoS One. 2016 Jun 13;11(6):e0157105.

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Analgesic Placebo Tanezumab - Hide

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CT-P13 comparable to infliximab at 54 weeks for ankylosing spondylitis

Arthritis Res Ther. 2016 Jan 20;18(1):25

RCT Spine Axial Skeleton Pain Spondylitis CELLTRION Janssen Infliximab CT-P13 - Hide

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Greater BMD increase with denosumab vs ZOL in patients switching from oral bisphosponates

J Clin Endocrinol Metab. 2016 Aug;101(8):3163-70

RCT Metabolic Disorders Osteoporosis Postmenopausal Women Amgen Denosumab Intravenous Injection Oral Subcutaneous Injections ZOL Zoledronic Acid - Hide

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Golimumab treatment provides superior treatment of rheumatoid arthritis

Lancet. 2009 Jul 18;374(9685):210-21. Epub 2009 Jun 26

RCT General Orthopaedics Tumour Arthritis Necrosis Golimumab Injection Inhibitor Placebo - Hide

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Long-term safety and effectiveness of tanezumab 10 mg vs. 20 mg for chronic low back pain

Pain. 2014 Sep;155(9):1793-801.

RCT General Orthopaedics Low Back Spine Back Pain Pfizer Intravenous Injections Of Tanezumab - Hide

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Intramedullary nailing of closed tibial fracture: rhBMP2-CPM augmentation not recommended

J Bone Joint Surg Am. 2013 Dec 4;95(23):2088-96. doi: 10.2106/JBJS.L.01545

RCT Trauma Bone Tibia Fracture Wyeth Augmentation Bone Morphogenetic Protein Calcium Phosphate CPM Fixation Locked Intramedullary Nail Matrix Reaming Recombinant SOC - Hide

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Extracorporeal Shockwave Therapy Using A Modified Technique on Tendon & Ligament for Knee OA

. 2022 01-Jan;():. 10.1097/PHM.0000000000001730

RCT Osteoarthritis Appendicular Lower Extremity Knee Bone Patella Tibia Joint Ligament Muscle Patellar Tendon Richard Wolf Electromagnetic Field Therapy Extracorporeal Shock Wave Therapy Transcutaneous Electrical Nerve Stimulation Sham Strength Training Electrical modality Piezowave 2 Piezowave 2 - Hide

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Lumbar fusion: rhBMP-2 reduces rate of fusion failure and reoperation

Arch Orthop Trauma Surg. 2012 Dec;132(12):1725-40. doi: 10.1007/s00402-012-1607-3. Epub 2012 Sep 1

Meta-analysis Spine Lumbar Bone Iliac Autogenous Iliac Crest Bone Graft Fusion ICBG Recombinant Human Bone Morphogenetic Protein-2 - Hide

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Perioperative administration of cyclooxygenase-2 inhibitors reduces pain in TKA patients

J Arthroplasty. 2013 Feb;28(2):207-213.e2. doi: 10.1016/j.arth.2012.04.008. Epub 2012 Jun 7

Meta-analysis Arthroplasty Lower Extremity Knee Pain Analgesia Opioid TKA - Hide

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Effect of Bamlanivimab (LY-CoV555) Antibody Treatment on Viral Load & Clinical Outcomes for COVID-19

No Clinical Benefit of LY-CoV555 Antibodies Plus Remdesivir in Hospitalized COVID-19 Patients

Juvenile RA: Fewer disease flares with Adalimumab (TNF Antibody)

Tocilizumab treatment in systemic juvenile idiopathic arthritis

Tanezumab effectively and safely reduces OA hip pain and improves physical function

Lower incidence of vertebral fracture with romosozumab vs placebo for osteoporosis

Support for physical distancing, face masks, and eye protection to prevent transmission of COVID-19

Salmon calcitonin appears ineffective in the management of knee OA treatment in 2 RCTs

Diclofenac, ibuprofen, and celecoxib improve function and pain in knee OA patients

Romosozumab versus placebo, alendronate, and teriparatide for postmenopausal osteoporosis

Canakinumab effective in treating systemic juvenile idiopathic arthritis

Efficacy of tanezumab vs. placebo on pain, function, safety for patients with knee OA

CT-P13 comparable to infliximab at 54 weeks for ankylosing spondylitis

Greater BMD increase with denosumab vs ZOL in patients switching from oral bisphosponates

Golimumab treatment provides superior treatment of rheumatoid arthritis

Long-term safety and effectiveness of tanezumab 10 mg vs. 20 mg for chronic low back pain

Intramedullary nailing of closed tibial fracture: rhBMP2-CPM augmentation not recommended

Extracorporeal Shockwave Therapy Using A Modified Technique on Tendon & Ligament for Knee OA

Lumbar fusion: rhBMP-2 reduces rate of fusion failure and reoperation

Perioperative administration of cyclooxygenase-2 inhibitors reduces pain in TKA patients

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