The efficacy & safety of various doses of fulranumab vs placebo for chronic LBP

Clin Ther. 2016 Jun;38(6):1435-50

Hyaluronic acid injection similar in symptom & structure of knee OA vs diacerein & placebo

Ann Rheum Dis. 2004 Dec;63(12):1611-7

Single-dose intra-articular bupivacaine significantly reduces pain after knee arthroscopy

Knee Surg Sports Traumatol Arthrosc. 2014 Jul;22(7):1517-28

Glucosamine + chondroitin reduced joint space narrowing at 2 years vs. placebo in knee OA

Ann Rheum Dis. 2015 May;74(5):851-8.

Delta-9 THC Improves Pain and Spasticity Compared to Placebo for Multiple Sclerosis Over 2 Weeks

CMAJ. 2012 Jul 10;184(10):1143-50. https://dx.doi.org/10.1503/cmaj.110837

WCO-IOF 2016: Lasofoxifene, raloxifene, and placebo for BMD in postmenopausal women

Dronabinol increases pain threshold compared to placebo for functional chest pain over 4 weeks

Dis Esophagus. 2017 Feb 1;30(2):1-8. doi: 10.1111/dote.12455

OARSI 2016: Glucosamine and chondroitin not more effective than placebo for knee OA

Chrondroitin sulfate improves pain and function compared to placebo in the management of knee OA

Ann Rheum Dis. 2017 May 22. pii: annrheumdis-2016-210860. doi: 10.1136/annrheumdis-2016-210860. [Epub ahead of print]

AAOS: Hyaluronic acid and placebo produce similar pain and functional outcomes for knee OA

Capsaicin provide comparable or better pain and functional improvement than placebo

Clin Drug Investig. 2011 Dec 1;31(12):877-82. doi: 10.2165/11593860-000000000-00000

Comparable efficacy with etoricoxib 30mg and ibuprofen 2400mg in treating hip or knee OA

Osteoarthritis Cartilage. 2007 Dec;15(12):1348-56. Epub 2007 Jul 16

Nabiximols improves multiple sclerosis spasticity compared to placebo over 12 weeks

Eur J Neurol. 2011 Sep;18(9):1122-31. doi: 10.1111/j.1468-1331.2010.03328.x

Titrated THC:CBD Improves Pain and Spasticity Compared to Placebo Over 12 Weeks for Resistant MS

Int J Neurosci. 2018 Sep 13:1-10.

Diclofenac versus acetaminophen versus placebo for treatment of symptomatic knee osteoarthritis

Arch Intern Med. 2003 Jan 27;163(2):169-78

AAOS 2016: High-dose hyaluronate reduces pain versus placebo for plantar fasciitis

Vertebroplasty for osteoporotic fractures yield no benefit over placebo at 2-years

J Bone Miner Res. 2014 Jun;29(6):1346-55.

Delta 9-THC has better analgesic efficacy versus placebo for neuropathic pain over 6 hours

J Pain. 2008 Jun;9(6):506-21. doi: 10.1016/j.jpain.2007.12.010

WCO-IOF: Dynamic electroneurostimulation vs placebo for osteoporotic spine fractures

Extended-release triamcinolone acetonide (FX006) versus placebo in knee osteoarthritis treatment

J Bone Joint Surg Am. 2018 Apr 18;100(8):666-677