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Potential efficacy of low-molecular-weight heparin in preventing thromboembolic events

Arthroscopy. 2014 Aug;30(8):987-96

Meta-analysis Trauma Anterior Cruciate LMWH Low-Molecular-Weight Heparin Meniscectomy Mobility Orthopaedic Placebo Preventing Prevention Prophylactic Reconstruction Thromboprophylaxis - Hide

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OTA 2022: Aspirin vs Low-Molecular-Weight Heparin for Thromboprophylaxis

RCT Trauma Appendicular Lower Extremity Lower Extremity Pelvis Joint Acetabulum Fracture Enoxaparin Aspirin Low-Molecular-Weight Heparin - Hide

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Asymptomatic DVT reduced, no reduction in symptomatic VTE with LMWH vs control in knee arthroscopy

PLoS One. 2018 Jun 21;13(6):e0197868

Meta-analysis Sports Medicine Thromboembolism Lower Extremity Knee Arthroscopic Surgery Arthroscopy Control LMWH Low-Molecular-Weight Heparin Reduction Thromboprophylaxis - Hide

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Routine thromboprophylaxis appears unnecessary following knee arthroscopy and lower-leg casting

N Engl J Med. 2017 Feb 9;376(6):515-525.

RCT General Orthopaedics Lower Extremity Knee Lower Leg Joint Meniscus Heparin Anticoagulant Therapy Arthroscopy Casting Thromboprophylaxis - Hide

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Portable compression device in addition to LMWH lowers DVT rate after TKA

J Arthroplasty. 2008 Dec;23(8):1122-7. Epub 2008 Apr 2

RCT Arthroplasty Lower Extremity Hip Knee Medical Compression Systems CECT Compression Enhanced LMWH Low-Molecular-Weight Heparin Portable TKA - Hide

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THA: Heparin does not stop pelvic thrombi but may prevent ipsilateral femoral thrombi

J Arthroplasty. 2005 Jan;20(1):42-50

RCT Arthroplasty Lower Extremity Hip Pelvis Bone Femur Heparin Injection Saline THA - Hide

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Mobile compression device vs. heparin for prevention of thromboembolic events after THA

J Bone Joint Surg Am. 2010 Mar;92(3):527-35

RCT Arthroplasty Thromboembolism Lower Extremity Hip Medical Compression Systems Enoxaparin CECT Low-Molecular-Weight Heparin Mobile Compression Prevention - Hide

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AAOS2019: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

RCT Trauma Thromboembolism Lower Extremity Pelvis Joint Acetabulum Fracture Aspirin LMWH Low Molecular Weight Heparin Prophylaxis - Hide

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Major orthopedic surgery: Low-molecular-weight heparins vs other anticoagulants

Pharmacotherapy. 2012 Sep;32(9):799-808. doi: 10.1002/j.1875-9114.2012.01106.x. Epub 2012 Jun 28

Meta-analysis General Orthopaedics Orthopaedic Surgery Anticoagulant Contact LMWH Low-Molecular-Weight Orthopedic Prevent Prophylactic - Hide

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OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

RCT Trauma Thromboembolism Lower Extremity Pelvis Joint Acetabulum Fracture Aspirin LMWH Low Molecular Weight Heparin Prophylaxis - Hide

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Low-Molecular Weight Heparin and Aspirin Provide Similar VTE Prevention in Trauma Fracture Patients

PloS one. 2020 Aug-03;():. 10.1371/journal.pone.0235628

RCT General Orthopaedics

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Low-molecular-weight heparin prophylaxis may reduce DVT incidence after knee arthroscopy

Arthroscopy. 2014 Mar;30(3):406-12. doi: 10.1016/j.arthro.2013.12.021.

Meta-analysis General Orthopaedics Lower Extremity Knee Arthroscopic Arthroscopy IV LMWH Low-Molecular-Weight Heparin Prevent Prophylaxis - Hide

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Delayed LMWH lowers bleeding while maintaining DVT prophylaxis in TKA

Arch Orthop Trauma Surg. 2014 May;134(5):679-83. doi: 10.1007/s00402-014-1939-2. Epub 2014 Feb 18

RCT Arthroplasty Wound Lower Extremity Knee Enoxaparin Heparin Delayed LMWH TKA Wound Closure - Hide

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OTA2018: Comparing efficacy between various VTE prophylaxis strategies after orthopaedic trauma

Meta-analysis Trauma Thromboembolism Appendicular Lower Extremity Heparin Acid Control Factor LMWH Mechanical Compression Molecular Weight Oral Orthopaedic Prophylaxis Thromboprophylaxis - Hide

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COA-ACO2018: Network metaanalysis of thromboprophylaxis strategies after lower extremity trauma

Meta-analysis Trauma Thromboembolism Appendicular Lower Extremity Heparin Acid Factor LMWH Mechanical Compression Molecular Weight Oral Orthopaedic Prophylaxis Thromboprophylaxis - Hide

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TKA prophylaxis: Risk-dependent anticoagulation safer than routine anticoagulation

J Arthroplasty. 2013 Dec;28(10):1868-73. doi: 10.1016/j.arth.2013.05.025. Epub 2013 Jun 21.

RCT Arthroplasty Lower Extremity Knee Heparin Aspirin Prophylaxis TKA - Hide

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Preventing Venous Thromboembolism after THA

JAMA. 1994: 271(22): 1780-1785.

Meta-analysis Arthroplasty Thromboembolism Lower Extremity Hip Heparin Aspirin Warfarin Compression Stockings Control Preventing Prophylaxis Prosthesis Replacement THA - Hide

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Extended thromboprophylaxis with aspirin noninferior to dalteparin for THA patients

Ann Intern Med. 2013 Jun 4;158(11):800-6. doi: 10.7326/0003-4819-158-11-201306040-00004

RCT Arthroplasty Thromboembolism Lower Extremity Hip Bayer Pfizer Low-Molecular-Weight Heparin Placebo Aspirin Placebo Dalteparin Injections THA Thromboprophylaxis - Hide

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COA: Extended thromboprophylaxis effective following hip fracture surgery

RCT General Orthopaedics Thromboembolism Lower Extremity Hip Fracture Injections Placebo Semuloparin Thromboprophylaxis - Hide

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Oral anticoagulants/LMW heparins provide comparable safety in antithrombotic prophylaxis

Semin Thromb Hemost. 2016 Feb;42(1):42-54

Meta-analysis General Orthopaedics Orthopaedic Surgery Lower Extremity Hip Knee Fracture /Fondaparinux Enhanced LMWH Low Molecular Weight Heparin Oral Orthopaedic Orthopedic Prophylaxis Replacement - Hide

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Potential efficacy of low-molecular-weight heparin in preventing thromboembolic events

OTA 2022: Aspirin vs Low-Molecular-Weight Heparin for Thromboprophylaxis

Asymptomatic DVT reduced, no reduction in symptomatic VTE with LMWH vs control in knee arthroscopy

Routine thromboprophylaxis appears unnecessary following knee arthroscopy and lower-leg casting

Portable compression device in addition to LMWH lowers DVT rate after TKA

THA: Heparin does not stop pelvic thrombi but may prevent ipsilateral femoral thrombi

Mobile compression device vs. heparin for prevention of thromboembolic events after THA

AAOS2019: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

Major orthopedic surgery: Low-molecular-weight heparins vs other anticoagulants

OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

Low-Molecular Weight Heparin and Aspirin Provide Similar VTE Prevention in Trauma Fracture Patients

Low-molecular-weight heparin prophylaxis may reduce DVT incidence after knee arthroscopy

Delayed LMWH lowers bleeding while maintaining DVT prophylaxis in TKA

OTA2018: Comparing efficacy between various VTE prophylaxis strategies after orthopaedic trauma

COA-ACO2018: Network metaanalysis of thromboprophylaxis strategies after lower extremity trauma

TKA prophylaxis: Risk-dependent anticoagulation safer than routine anticoagulation

Preventing Venous Thromboembolism after THA

Extended thromboprophylaxis with aspirin noninferior to dalteparin for THA patients

COA: Extended thromboprophylaxis effective following hip fracture surgery

Oral anticoagulants/LMW heparins provide comparable safety in antithrombotic prophylaxis

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