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Hyaluronic acid versus corticosteroid in the treatment of knee osteoarthritis

ACE Review Osteoarthritis

Knee OA - The therapeutic trajectory of corticosteroids and hyaluronic acid

Arthritis Rheum. 2009 Dec 15;61(12):1704-11

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Hyaluronan Corticosteroid Injections Conservative Hyaluronate Hyaluronic Acid Injections Intraarticular Injections Of Hyaluronic Acid Post-Injection Viscosupplementation - Hide

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Efficacy of hyaluronic acid vs placebo for pain relief in knee OA; meta-analysis of RCTs

J Fam Pract. 2005 Sep;54(9):758-67

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Hyaluronic Acid Injections Injections Of Hyaluronic Acid Injections Of Placebo Saline Injection - Hide

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Intra-articular hyaluronic acid provides longer pain relief as compared to corticosteroid

Exp Ther Med. 2015 Feb;9(2):493-500.

Meta-analysis General Orthopaedics Osteoarthritis Lower Extremity Knee Arthritis Pain Hyaluronan Corticosteroid Flexion HA Hyaluronic Acid Injection Injections Of Hyaluronic Acid - Hide

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Small effect of hyaluronic acid for pain relief in treatment of knee osteoarthrits

JAMA. 2003 Dec 17;290(23):3115-21

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Synvisc Orthovisc Hyaluronic Acid Injections Injections Of Hyaluronic Acid Placebo - Hide

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Differences in hyaluronic acid characteristics influence outcomes in knee OA patients

Am J Sports Med. 2016 Aug;44(8):2158-65

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Ferring Hylan Hyaluronan Hyaluronic Acid Injections Viscosupplementation - Hide

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Limited efficacy of intra-articular hyaluronic acid in treatment of knee OA

CMAJ. 2005 Apr 12;172(8):1039-43

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Hyaluronan Hyaluronate Hyaluronic Acid Injections Placebo Injections Rest Viscosupplementation - Hide

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Improvement of condition with hyaluronic acid injection for ankle OA

Arch Phys Med Rehabil. 2013 May;94(5):951-60. doi: 10.1016/j.apmr.2012.10.030. Epub 2012 Nov 10

Meta-analysis Osteoarthritis Lower Extremity Ankle Arthritis HA Hyaluronic Acid Injections Viscosupplementation - Hide

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Analysis of efficacy of different hyaluronic acid products in treatment of knee OA

BioDrugs. 2012 Aug 1;26(4):257-68

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Consultation Current Hyaluronic Acid Placebo - Hide

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Hyaluronic acid vs corticoid injections for osteoarthritis of the first carpometacarpal

Joint Bone Spine. 2015 Mar;82(2):116-21.

RCT Osteoarthritis Joint Carpometacarpal Arthritis Betamethasone Injections Hyaluronic Acid - Hide

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Hyaluronic acid and exercise therapy, in combination or as monotherapy, for knee OA

Knee Surg Sports Traumatol Arthrosc. 2016 May;24(5):1686-94

RCT Physical Therapy & Rehab Osteoarthritis Lower Extremity Knee Arthritis Anika Exercise Hyaluronic Acid Injections Monotherapy Rehabilitation - Hide

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AAOS: Reporting of hyaluronic acid efficacy in knee OA may be influenced by industry

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Hyaluronic Acid Injections Placebo - Hide

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HA more effective than placebo in knee OA, no difference between 3 and 6 injections of HA

. 2006 ;():.

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Bioniche Injections HA Injection Hyaluronic Acid Placebo - Hide

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OARSI 2016: Similar pain relief between combined hyaluronic acid(HA)/mannitol and high MW

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Mannitol Injections HA High Molecular Weight Hyaluronic Acid Intermediate Molecular Weight Hyaluronic Acid - Hide

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Consistent pain improvement from 4-24 weeks with hyaluronic acid in knee osteoarthritis

Osteoarthritis Cartilage. 2011 Jun;19(6):611-9

Meta-analysis Osteoarthritis Lower Extremity Knee Arthritis Pain Hylan Hyaluronan Synvisc Orthovisc Injections Hyaluronate Hyaluronic Acid Injection IA Placebo IAHA Viscosupplementation - Hide

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Pain reduction greater with 5 injections of high-dose HA vs control for plantar fasciopathy

Knee Surg Sports Traumatol Arthrosc. 2018 Mar;26(3):903-911

RCT Foot & Ankle Lower Extremity Muscle Plantar Fascia Pain Chugai Pharmaceutical Injections Control High-Dose HA Hyaluronic Acid Low-Dose Reduction - Hide

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Better early outcome, similar 6-12 month outcome with PRP versus HA for hip osteoarthritis

Int J Surg. 2018 May;53:279-287

Meta-analysis Osteoarthritis Lower Extremity Hip Arthritis HA Hyaluronic Acid Injections Platelet-Rich Plasma Injections Post-Injection PRP - Hide

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Improved articular cartilage repair with combined stem cell and hyaluronic acid injection

Arthroscopy. 2013 Apr;29(4):684-94. doi: 10.1016/j.arthro.2012.12.008. Epub 2013 Feb 4

RCT Sports Medicine Lesion Lower Extremity Knee Cartilage Arthroscopic Subchondral Drilling Injections Of Hyaluronic Acid Peripheral Blood Stem Cells - Hide

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IA versus oral hyaluronic acid in the treatment of patients with KL grade I-II knee osteoarthritis

Musculoskelet Surg. 2017 Apr;101(1):45-49. doi: 10.1007/s12306-016-0428-x

RCT Osteoarthritis Lower Extremity Knee Arthritis Hyaluronic Acid IAHA Oral - Hide

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Hyaluronic acid injections reduce IL-1B and severity of knee OA after 5 weeks

Pak J Pharm Sci. 2015 Jan;28(1 Suppl):407-10.

RCT Osteoarthritis Lower Extremity Knee Arthritis Fluid Hyaluronic Acid Injections Placebo - Hide

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Hyaluronic acid versus corticosteroid in the treatment of knee osteoarthritis

Knee OA - The therapeutic trajectory of corticosteroids and hyaluronic acid

Efficacy of hyaluronic acid vs placebo for pain relief in knee OA; meta-analysis of RCTs

Intra-articular hyaluronic acid provides longer pain relief as compared to corticosteroid

Small effect of hyaluronic acid for pain relief in treatment of knee osteoarthrits

Differences in hyaluronic acid characteristics influence outcomes in knee OA patients

Limited efficacy of intra-articular hyaluronic acid in treatment of knee OA

Improvement of condition with hyaluronic acid injection for ankle OA

Analysis of efficacy of different hyaluronic acid products in treatment of knee OA

Hyaluronic acid vs corticoid injections for osteoarthritis of the first carpometacarpal

Hyaluronic acid and exercise therapy, in combination or as monotherapy, for knee OA

AAOS: Reporting of hyaluronic acid efficacy in knee OA may be influenced by industry

HA more effective than placebo in knee OA, no difference between 3 and 6 injections of HA

OARSI 2016: Similar pain relief between combined hyaluronic acid(HA)/mannitol and high MW

Consistent pain improvement from 4-24 weeks with hyaluronic acid in knee osteoarthritis

Pain reduction greater with 5 injections of high-dose HA vs control for plantar fasciopathy

Better early outcome, similar 6-12 month outcome with PRP versus HA for hip osteoarthritis

Improved articular cartilage repair with combined stem cell and hyaluronic acid injection

IA versus oral hyaluronic acid in the treatment of patients with KL grade I-II knee osteoarthritis

Hyaluronic acid injections reduce IL-1B and severity of knee OA after 5 weeks

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