Aspirin reduces risk of recurrence in patients with unprovoked venous thromboembolism

N Engl J Med. 2012 May 24;366(21):1959-67. doi: 10.1056/NEJMoa1114238

OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

POISE 2 (Part 1): The safety and efficacy of aspirin following non-cardiac surgery

N Engl J Med. 2014 Apr 17;370(16):1494-503. doi: 10.1056/NEJMoa1401105. Epub 2014 Mar 31

OTA2017: Compliance similar between aspirin & enoxaparin in VTE prophylaxis after orthopaedic trauma

AAOS2018: Additional compression pump to aspirin for thromboprophylaxis after TJA unnecessary

Perioperative aspirin reduces major cardiac adverse events following non-cardiac surgery

Br J Anaesth. 2010 Mar;104(3):305-12. doi: 10.1093/bja/aeq003.

AAOS2019: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

Enoxaparin does not significantly reduce rates of deep vein thrombosis after TKA

J Arthroplasty. 2006 Sep;21(6 Suppl 2):139-43.

COA-ACO2018: Comparison of VTE prophylaxis of aspirin vs. extended rivaroxaban after TKA/THA

No significant difference in DVT incidence between aspirin vs rivaroxaban in total knee arthroplasty

Rev Bras Ortop. 2017 Dec 6;53(1):22-27

Similar extended VTE prophylaxis efficacy and safety between rivaroxaban and aspirin following TJA

N Engl J Med. 2018 Feb 22;378(8):699-707

Extended thromboprophylaxis with aspirin noninferior to dalteparin for THA patients

Ann Intern Med. 2013 Jun 4;158(11):800-6. doi: 10.7326/0003-4819-158-11-201306040-00004

ISAKOS2017: Comparison of mechanical vs chemical thromboprophylaxis, including administration timing

AAOS: Fondaparinux appears to be associated with elevated blood coagulation factors

Mechanical compression effective in reduction of thrombosis after hip arthroplasty

Ryan MG, Westrich GH, Potter HG, Sharrock N, Maun LM, Macaulay W, Katkin P, Sculco TP, Salvati EA.

ISAKOS 2015: 10 day Rivaroxaban reduces venous thromboembolism 3 months after TKA

Preventing Venous Thromboembolism after THA

JAMA. 1994: 271(22): 1780-1785.

AAOS: Lower preoperative coagulation factors may correlate with transfusion risk in TJA

POISE 2 (Part 2): The safety and efficacy of clonidine following non-cardiac surgery

N Engl J Med. 2014 Apr 17;370(16):1504-13. doi: 10.1056/NEJMoa1401106. Epub 2014 Mar 31.

TKA prophylaxis: Risk-dependent anticoagulation safer than routine anticoagulation

J Arthroplasty. 2013 Dec;28(10):1868-73. doi: 10.1016/j.arth.2013.05.025. Epub 2013 Jun 21.