Aspirin reduces risk of recurrence in patients with unprovoked venous thromboembolism

N Engl J Med. 2012 May 24;366(21):1959-67. doi: 10.1056/NEJMoa1114238

OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

POISE 2 (Part 1): The safety and efficacy of aspirin following non-cardiac surgery

N Engl J Med. 2014 Apr 17;370(16):1494-503. doi: 10.1056/NEJMoa1401105. Epub 2014 Mar 31

AAOS2018: Additional compression pump to aspirin for thromboprophylaxis after TJA unnecessary

OTA2017: Compliance similar between aspirin & enoxaparin in VTE prophylaxis after orthopaedic trauma

Perioperative aspirin reduces major cardiac adverse events following non-cardiac surgery

Br J Anaesth. 2010 Mar;104(3):305-12. doi: 10.1093/bja/aeq003.

Enoxaparin does not significantly reduce rates of deep vein thrombosis after TKA

J Arthroplasty. 2006 Sep;21(6 Suppl 2):139-43.

AAOS2019: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

OTA 2022: Aspirin vs Low-Molecular-Weight Heparin for Thromboprophylaxis

Similar extended VTE prophylaxis efficacy and safety between rivaroxaban and aspirin following TJA

N Engl J Med. 2018 Feb 22;378(8):699-707

COA-ACO2018: Comparison of VTE prophylaxis of aspirin vs. extended rivaroxaban after TKA/THA

No significant difference in DVT incidence between aspirin vs rivaroxaban in total knee arthroplasty

Rev Bras Ortop. 2017 Dec 6;53(1):22-27

ISAKOS2017: Comparison of mechanical vs chemical thromboprophylaxis, including administration timing

Extended thromboprophylaxis with aspirin noninferior to dalteparin for THA patients

Ann Intern Med. 2013 Jun 4;158(11):800-6. doi: 10.7326/0003-4819-158-11-201306040-00004

AAOS: Fondaparinux appears to be associated with elevated blood coagulation factors

Aspirin or Rivaroxaban for Preventing Venous Thromboembolism after Total Knee Arthroplasty

Rev Bras Ortop (Sao Paulo). 2022 01-Oct;():. 10.1055/s-0041-1735941

Aspirin vs. Enoxaparin for Preventing Symptomatic Venous Thromboembolism in Hip or Knee Arthroplasty

JAMA. 2022 Aug 23;328(8):719-727. doi: 10.1001/jama.2022.13416.. 2022 01-Aug;():. 10.1001/jama.2022.13416

Mechanical compression effective in reduction of thrombosis after hip arthroplasty

Ryan MG, Westrich GH, Potter HG, Sharrock N, Maun LM, Macaulay W, Katkin P, Sculco TP, Salvati EA.

Similar Adverse Events & Complications with Aspirin vs Enoxparin for Hip/Knee Arthroplasty Patients

Orthop Traumatol Surg Res. 2021 01-Feb;():. 10.1016/j.otsr.2020.04.002

100 mg Aspirin Twice Daily Non-Inferior to Once Daily 10 mg Rivaroxaban for Prevention of VTE in THA

Chin Med J (Engl). 2021 05-Jan;():. 10.1097/CM9.0000000000001305