Aspirin reduces risk of recurrence in patients with unprovoked venous thromboembolism

N Engl J Med. 2012 May 24;366(21):1959-67. doi: 10.1056/NEJMoa1114238

OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

POISE 2 (Part 1): The safety and efficacy of aspirin following non-cardiac surgery

N Engl J Med. 2014 Apr 17;370(16):1494-503. doi: 10.1056/NEJMoa1401105. Epub 2014 Mar 31

AAOS2018: Additional compression pump to aspirin for thromboprophylaxis after TJA unnecessary

Perioperative aspirin reduces major cardiac adverse events following non-cardiac surgery

Br J Anaesth. 2010 Mar;104(3):305-12. doi: 10.1093/bja/aeq003.

OTA2017: Compliance similar between aspirin & enoxaparin in VTE prophylaxis after orthopaedic trauma

AAOS2019: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

Enoxaparin does not significantly reduce rates of deep vein thrombosis after TKA

J Arthroplasty. 2006 Sep;21(6 Suppl 2):139-43.

Similar extended VTE prophylaxis efficacy and safety between rivaroxaban and aspirin following TJA

N Engl J Med. 2018 Feb 22;378(8):699-707

COA-ACO2018: Comparison of VTE prophylaxis of aspirin vs. extended rivaroxaban after TKA/THA

No significant difference in DVT incidence between aspirin vs rivaroxaban in total knee arthroplasty

Rev Bras Ortop. 2017 Dec 6;53(1):22-27

Extended thromboprophylaxis with aspirin noninferior to dalteparin for THA patients

Ann Intern Med. 2013 Jun 4;158(11):800-6. doi: 10.7326/0003-4819-158-11-201306040-00004

Mechanical compression effective in reduction of thrombosis after hip arthroplasty

Ryan MG, Westrich GH, Potter HG, Sharrock N, Maun LM, Macaulay W, Katkin P, Sculco TP, Salvati EA.

AAOS: Fondaparinux appears to be associated with elevated blood coagulation factors

ISAKOS2017: Comparison of mechanical vs chemical thromboprophylaxis, including administration timing

ISAKOS 2015: 10 day Rivaroxaban reduces venous thromboembolism 3 months after TKA

AAOS: Lower preoperative coagulation factors may correlate with transfusion risk in TJA

Preventing Venous Thromboembolism after THA

JAMA. 1994: 271(22): 1780-1785.

POISE 2 (Part 2): The safety and efficacy of clonidine following non-cardiac surgery

N Engl J Med. 2014 Apr 17;370(16):1504-13. doi: 10.1056/NEJMoa1401106. Epub 2014 Mar 31.

TKA prophylaxis: Risk-dependent anticoagulation safer than routine anticoagulation

J Arthroplasty. 2013 Dec;28(10):1868-73. doi: 10.1016/j.arth.2013.05.025. Epub 2013 Jun 21.