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Prolonged use of corticosteroid injections for knee osteoarthritis reduces cartilage volume

JAMA. 2017 May 16;317(19):1967-1975

RCT Osteoarthritis Lower Extremity Knee Arthritis Cartilage Pain Synovitis Injections Corticosteroid Saline Triamcinolone Acetonide - Hide
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IA glucocorticioid not associated with decrease in synovitis when compared to IA saline for knee OA

Osteoarthritis Cartilage. 2017 Apr;25(4):481-491

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Synovitis Methylprednisolone Lidocaine Glucocorticoid Injection IA Saline Ultrasound-Guided - Hide
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Knee OA: MRI assessments reveal early effect of chondroitin sulphate on cartilage loss

Ann Rheum Dis. 2011 Jun;70(6):982-9. doi: 10.1136/ard.2010.140848. Epub 2011 Mar 1

RCT Osteoarthritis Lesion Lower Extremity Knee Arthritis Cartilage Swelling Synovitis Bioiberica Bone Marrow Chondroitin Sulphate MRI Placebo - Hide
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