
Neither additional IV nor oral acetaminophen enhances multimodal analgesia efficacy in TKA

Neither additional IV nor oral acetaminophen enhances multimodal analgesia efficacy in TKA
Intravenous vs Oral Acetaminophen as an Adjunct to Multimodal Analgesia After Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind Clinical Trial
J Arthroplasty. 2017 Oct;32(10):3029-3033Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
174 patients scheduled for primary unilateral total knee arthroplasty were randomized to postoperative intravenous acetaminophen, postoperative oral acetaminophen, or postoperative placebo, all of these treatments were given in addition to a multimodal analgesia regimen. Patients were assessed for analgesia outcomes, including pain scores and opioid consumption, within the postanaesthesia care uni...
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