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Meta-analysis
ACE Report #9809
Ace Report Cover Osteoarthritis

Assessing the efficacy of topical diclofenac in the treatment of knee osteoarthritis pain


Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A

Pennsaid therapy for osteoarthritis of the knee: a systematic review and metaanalysis of randomized controlled trials

J Rheumatol. 2006 Mar;33(3):567-73

Contributing Authors: TE Towheed

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Synopsis

Four randomized controlled trials were included in this meta-analysis comparing the efficacy of a specific preparation of topical diclofenac, Pennsaid, to either placebo or oral diclofenac in the treatment of knee osteoarthritis. As compared to placebo, Pennsaid topical diclofenac was associated with significantly better clinical results of the Western Ontario and McMaster Universities Osteoarthri...

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