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Chrondroitin sulfate improves pain and function compared to placebo in the management of knee OA
June 2017
Chrondroitin sulfate improves pain and function compared to placebo in the management of knee OA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Pharmaceutical-grade Chondroitin sulfate is as effective as celecoxib and superior to placebo in symptomatic knee osteoarthritis: the ChONdroitin versus CElecoxib versus Placebo Trial (CONCEPT)
Ann Rheum Dis. 2017 May 22. pii: annrheumdis-2016-210860. doi: 10.1136/annrheumdis-2016-210860. [Epub ahead of print]Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
604 patients with symptomatic knee osteoarthritis were randomized to treatment with either chondroitin sulfate, celecoxib, or placebo over a 6 month period. Patients were assessed for pain, function, perceived improvement and adverse events over the 6 months. The results from this study indicated that all three groups demonstrated a significant improvement from baseline over the 6 months. Both the...
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