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TXA effective in reducing blood loss in mini-invasive TKA with postoperative rivaroxaban

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Ace Report Cover
November 2017

TXA effective in reducing blood loss in mini-invasive TKA with postoperative rivaroxaban

Vol: 6| Issue: 11| Number:17| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

The Efficacy of Combined Use of Rivaroxaban and Tranexamic Acid on Blood Conservation in Minimally Invasive Total Knee Arthroplasty a Double-Blind Randomized, Controlled Trial

J Arthroplasty. 2017 Mar;32(3):801-806

Contributing Authors:
PC Lin CC Huang JW Wang B Chen FC Kuo SH Yen

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Synopsis

200 patients scheduled for minimally invasive total knee arthroplasty and thromboprophylaxis with rivaroxaban were randomized to either intravenous tranexamic acid or placebo. Patients were assessed for blood loss, transfusion rate, hemoglobin levels, rates of ecchymosis, wound hematoma, and deep infection. Total blood loss was significantly lower in the TXA group compared to placebo, while no sig...

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