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RCT
ACE Report #9609
Ace Report Cover Arthroplasty

No significant analgesic benefit of liposomal bupivacaine over bupivacaine HCl for PAI in TJA


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Periarticular Injection of Liposomal Bupivacaine Offers No Benefit Over Standard Bupivacaine in Total Knee Arthroplasty: A Prospective, Randomized, Controlled Trial

J Arthroplasty. 2017 Feb;32(2):628-634

Contributing Authors: J Parvizi RH Rothman JJ Purtill MS Austin P Alijanipour JR Viola TL Tan CN Matthews

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Synopsis

162 patients scheduled for total knee arthroplasty were randomized to postoperative analgesia using periarticular injection analgesia containing either liposomal bupivacaine or standard bupivacaine HCl. The purpose of this study was to determine if the use of liposomal bupivacaine was associated with significantly lower perioperative pain scores. Results demonstrated no significant differences bet...

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